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[增殖刺激因子对急性四氯化碳中毒大鼠血清胆固醇酯化的影响]

[Effect of proliferation-stimulating factors on cholesterol esterification in the serum of rats with acute tetrachloromethane poisoning].

作者信息

Chirkin A A, Konevalova N Iu

出版信息

Vopr Med Khim. 1987 Nov-Dec;33(6):124-8.

PMID:3328413
Abstract

Three phases of cholesterolemia were detected in rats after single administration of CCl4 at a dose of 0.3 ml of oil solution per 100 g of body mass. Factors, stimulating proliferation of hepatocytes and isolated from regenerating liver tissue, did not affect the type of cholesterolemia whereas they stimulated cholesterol esters formation in circulation.

摘要

以每100克体重0.3毫升油溶液的剂量给大鼠单次注射四氯化碳后,检测到大鼠出现了三个阶段的胆固醇血症。从再生肝组织中分离出的刺激肝细胞增殖的因子,并不影响胆固醇血症的类型,然而它们却刺激了循环中胆固醇酯的形成。

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