Konevalova N Iu, Chirkin A A
Nauchnye Doki Vyss Shkoly Biol Nauki. 1987(3):25-30.
The effect of proliferation stimulating factors (PSF) obtained from regenerating liver on the cholesterol esterification in blood serum under deep tetrachloromethane intoxication has been studied in experiments with white rats. Three phases in dynamics of cholesterol content in blood serum have been picked out after a single tetrachloromethane injection. The content of total cholesterol and cholesterol esters reduces during the first phase (24 h), during the second phase (3-7th day) it increases and during the third phase (15th day) these values become normal. PSF injection does not produce any influence on the nature of blood cholesterol under deep tetrachloromethane intoxication, but stimulates the processes of cholesterol ester formation in blood serum.
在对白鼠进行的实验中，研究了从再生肝脏中获得的增殖刺激因子（PSF）对四氯化碳深度中毒情况下血清中胆固醇酯化的影响。单次注射四氯化碳后，血清中胆固醇含量的动态变化呈现出三个阶段。在第一阶段（24小时），总胆固醇和胆固醇酯的含量降低；在第二阶段（第3 - 7天），其含量增加；而在第三阶段（第15天），这些数值恢复正常。在四氯化碳深度中毒情况下，注射PSF对血液中胆固醇的性质没有任何影响，但能刺激血清中胆固醇酯的形成过程。
