Guan Hui-Lin, Wang Yu, Gui Yi-Fang, Zhang Chun-Lei
Department of Scientific Research, Mudanjiang Medical University.
Department of Reproduction, Mudangjiang Women and Children Hospital.
Medicine (Baltimore). 2020 Dec 4;99(49):e23463. doi: 10.1097/MD.0000000000023463.
Data supporting the use of Chinese herbal medicine compound (CHMC) on breast hyperplasia (BH) based on the data from previous studies. However, the results are still contradictory. Thus, this study aims to compare the results obtained for effect on case-controlled study (CCS) of CHMC on BH.
This study will include CCS assessing the effect of CHMC on BH. A literature search will be carried out in Cochrane Library, MEDLINE, EMBASE, Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure from inception to the present. We will not apply language limitation to any electronic database. Study quality will be evaluated using Newcastle-Ottawa Scale, and statistical analysis will be performed using RevMan 5.3 software.
This study will summarize the up-to-date evidence to assess the effect of CHMC on BH.
The results of this study may exert helpful evidence to determine whether CHMC is effective on BH. OSF REGISTRATION NUMBER:: osf.io/3k8ch.
基于以往研究数据，有证据支持使用中药复方治疗乳腺增生症（BH）。然而，结果仍存在矛盾。因此，本研究旨在比较中药复方治疗乳腺增生症的病例对照研究（CCS）结果。
本研究将纳入评估中药复方治疗乳腺增生症效果的病例对照研究。从创刊至目前，将在Cochrane图书馆、MEDLINE、EMBASE、联合与补充医学数据库、中国生物医学文献数据库和中国知网进行文献检索。我们将不对任何电子数据库设置语言限制。使用纽卡斯尔-渥太华量表评估研究质量，并使用RevMan 5.3软件进行统计分析。
本研究将总结最新证据，以评估中药复方治疗乳腺增生症的效果。
本研究结果可能为确定中药复方对乳腺增生症是否有效提供有用证据。开放科学框架注册号：osf.io/3k8ch。
