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慢性肾脏病成人的有氧、抗阻及联合训练:一项系统评价与网状Meta分析方案

Aerobic, resistance and combined training for adults with chronic kidney disease: A protocol for a systematic review and network meta-analysis.

作者信息

Zeng Rong, Lai Honghao, Li Zhuoyan, Chen Beibei, Wang Lu, Zhang Yali

机构信息

Department of Nephrology, the Second Hospital.

School of Public Health, Lanzhou University.

出版信息

Medicine (Baltimore). 2020 Dec 4;99(49):e23518. doi: 10.1097/MD.0000000000023518.

DOI:10.1097/MD.0000000000023518
PMID:33285764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7717791/
Abstract

BACKGROUND

Chronic kidney disease (CKD) as a disease that poses a great threat to human health, which has become a public health issue of great concern. Studies have found that exercise training has a positive effect on improving the condition of chronic kidney disease. We will conduct a network meta-analysis to assess the effects of aerobic training, resistance training and combined aerobic and resistance training in treating CKD patients.

METHODS

We will search PubMed, EMBASE, Medline, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of science to identify randomized control trails (RCTs) that assessed the effect of different exercise training for CKD patients. Cochrane Handbook will be used to evaluate the risk of bias of included articles. We will use Stata or R software to perform data analysis.

RESULTS AND CONCLUSION

Our systematic review and network meta-analysis will be the first study that investigates the effect of different exercise training for CKD patients, and will provide evidence for management of chronic kidney disease.

ETHICS AND DISSEMINATION

The data involved in this study are from published articles. For this reason, there is no need for ethical approval or patient consent.

TRIAL REGISTRATION

the registration number was: CRD42020157280.

摘要

背景

慢性肾脏病(CKD)作为一种对人类健康构成重大威胁的疾病,已成为备受关注的公共卫生问题。研究发现,运动训练对改善慢性肾脏病病情有积极作用。我们将进行一项网状Meta分析,以评估有氧运动训练、抗阻训练以及有氧与抗阻联合训练对治疗CKD患者的效果。

方法

我们将检索PubMed、EMBASE、Medline、Cochrane对照试验中心注册库(CENTRAL)和科学网,以识别评估不同运动训练对CKD患者效果的随机对照试验(RCT)。将使用Cochrane手册评估纳入文章的偏倚风险。我们将使用Stata或R软件进行数据分析。

结果与结论

我们的系统评价和网状Meta分析将是第一项研究不同运动训练对CKD患者效果的研究,并将为慢性肾脏病的管理提供证据。

伦理与传播

本研究涉及的数据来自已发表的文章。因此,无需伦理批准或患者同意。

试验注册

注册号为:CRD42020157280。

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本文引用的文献

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The effects of aerobic exercise on eGFR, blood pressure and VO2peak in patients with chronic kidney disease stages 3-4: A systematic review and meta-analysis.有氧运动对慢性肾脏病 3-4 期患者 eGFR、血压和 VO2peak 的影响:系统评价和荟萃分析。
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