Guo Q S, Ruan P, Huang W X, Shen H T, Qiu J C
School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, China; Guangdong Province Engineering and Technology Research Center for Medical 3D Printer and Personalized Medicine, Guangzhou 510006, China.
Guangdong Province Engineering and Technology Research Center for Medical 3D Printer and Personalized Medicine, Guangzhou 510006, China ; Department of Biomedical Engineering, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2020 Nov 20;38(11):826-830. doi: 10.3760/cma.j.cn121094-20200120-00032.
To explore the association between long-term low-dose radiation exposure and other influencing factors with the risk of lens opacity on medical radiation workers. In July 2019, a retrospective cohort study was conducted by collecting the basic demographic information, dose data and health inspection result of 2708 radiologists in 22 hospitals of Guangzhou from the Occupational Health Inspection Information System and the Personal Dose Monitoring System of the Guangdong Prevention and Treatment Center for Occupational Disease between 2010 to 2018. The association between the average annual effective dose and lens opacity risk was calculated by using Time-Dependent Cox Regression Model. From 2010 to 2018, the incidence density of lens opacity was 185.90/10000 person years. Compared with the radiation workers in the age <30 years group (93.74%) , the 5-year normal rate of lens in the age ≥50 years group (72.51%) was lower (<0.01) ; Compared with the radiation workers in the exposure age <10 years group (92.69%) , the 5-year normal rate of lens in more than 20 years exposed group (83.05%) was lower (<0.01) . Multifactor analysis showed that age was an independent influencing factor for lens opacity in medical radiation workers (=14.485, <0.01) . The risk of lens opacification increased by 4.9%, 10.1% and 15.5% in 30-, 40- and 50-years group, respectively. Gender, cigarette, alchol, type of work, length of service and annual effective dose had no significant effect on lens opacity (>0.05) . Age is the main influencing factor of lens opacification in medical radiation workers, their radiation working time and intensity should be strictly controlled and radiation protection should be done.
探讨长期低剂量辐射暴露及其他影响因素与医学放射工作人员晶状体混浊风险之间的关联。2019年7月，通过从广东省职业病防治院职业健康检查信息系统和个人剂量监测系统收集2010年至2018年期间广州市22家医院2708名放射科医生的基本人口统计学信息、剂量数据和健康检查结果，进行了一项回顾性队列研究。采用时间依赖性Cox回归模型计算平均年有效剂量与晶状体混浊风险之间的关联。2010年至2018年，晶状体混浊的发病密度为185.90/10000人年。与年龄<30岁组的放射工作人员（93.74%）相比，年龄≥50岁组晶状体的5年正常率（72.51%）较低（<0.01）；与暴露年限<10年组的放射工作人员（92.69%）相比，暴露20年以上组晶状体的5年正常率（83.05%）较低（<0.01）。多因素分析显示，年龄是医学放射工作人员晶状体混浊的独立影响因素（=14.485，<0.01）。30岁、40岁和50岁组晶状体混浊的风险分别增加4.9%、10.1%和15.5%。性别、吸烟、饮酒、工作类型、服务年限和年有效剂量对晶状体混浊无显著影响（>0.05）。年龄是医学放射工作人员晶状体混浊的主要影响因素，应严格控制其放射工作时间和强度，并做好辐射防护。
