Pôle de Recherche en Gynécologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
Pôle de Recherche en Gynécologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium; Gynecology Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Reprod Biomed Online. 2021 Feb;42(2):351-365. doi: 10.1016/j.rbmo.2020.11.001. Epub 2020 Nov 9.
In recent years, some countries and fertility preservation networks have started adopting 24 h transportation for ovarian tissue, a practice that has the potential to spread very quickly due to the high costs and bureaucracy involved in the establishment of ovarian tissue cryobanks. While pregnancies and live births have been reported after such long periods of transportation, this, however, remains an empirical procedure. This review aims to prompt reflection on ovarian tissue transport, highlighting the lack of knowledge in humans by providing a counterpoint looking into more than 40 studies published in different animal models. By discussing these studies in animals, the findings of various models can be deciphered, and light shed on the patterns identified. Like the development of different assisted reproductive technology procedures, this is an important step in creating guidelines for future studies on human ovarian tissue transportation.
近年来，一些国家和生育保护网络开始采用 24 小时运输卵巢组织的方式，由于建立卵巢组织低温保存库涉及高昂的成本和官僚主义，这种做法很可能迅速传播。虽然有报道称在如此长的运输时间后成功怀孕并分娩，但这仍然是一种经验性的程序。本综述旨在通过提供一个在不同动物模型中发表的 40 多项研究的对照，促使人们对卵巢组织运输进行反思，强调人类对此缺乏了解。通过讨论这些动物研究，可以解释各种模型的发现，并阐明所确定的模式。就像不同辅助生殖技术程序的发展一样，这是为人类卵巢组织运输的未来研究制定指南的重要一步。
