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大流行期间的生物安全:共享资源实验室迎接挑战。

Biosafety during a pandemic: shared resource laboratories rise to the challenge.

机构信息

Sydney Cytometry Core Research Facility, Centenary Institute, The University of Sydney, Sydney, New South Wales, Australia.

Flow Cytometry Section, Research Technologies Branch, NIAID, NIH, Bethesda, Maryland, USA.

出版信息

Cytometry A. 2021 Jan;99(1):68-80. doi: 10.1002/cyto.a.24280. Epub 2021 Jan 4.

Abstract

Biosafety has always been an important aspect of daily work in any research institution, particularly for cytometry Shared Resources Laboratories (SRLs). SRLs are common-use spaces that facilitate the sharing of knowledge, expertise, and ideas. This sharing inescapably involves contact and interaction of all those within this working environment on a daily basis. The current pandemic caused by SARS-CoV-2 has prompted the re-evaluation of many policies governing the operations of SRLs. Here we identify and review the unique challenges SRLs face in maintaining biosafety standards, highlighting the potential risks associated with not only cytometry instrumentation and samples, but also the people working with them. We propose possible solutions to safety issues raised by the COVID-19 pandemic and provide tools for facilities to adapt to evolving guidelines and future challenges.

摘要

生物安全一直是任何研究机构日常工作的一个重要方面,对于细胞分析共享资源实验室(SRL)尤其如此。SRL 是通用空间,可促进知识、专业知识和思想的共享。这种共享不可避免地涉及到日常工作环境中所有人员的接触和互动。由 SARS-CoV-2 引起的当前大流行促使人们重新评估了许多管理 SRL 运营的政策。在这里,我们确定并审查了 SRL 在维持生物安全标准方面面临的独特挑战,突出了不仅与细胞分析仪器和样本相关,而且与与之合作的人员相关的潜在风险。我们提出了针对 COVID-19 大流行引起的安全问题的可能解决方案,并为设施提供了适应不断变化的指南和未来挑战的工具。

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