遗尿与儿童阻塞性睡眠呼吸暂停低通气综合征的关系。
Relationship between enuresis and obstructive sleep apnea-hypopnea syndrome in children.
机构信息
Department of ENT, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Medical School of Nanjing University, Nanjing, Jiangsu, China.
出版信息
J Int Med Res. 2020 Dec;48(12):300060520977407. doi: 10.1177/0300060520977407.
OBJECTIVE
We explored the relationship between enuresis and obstructive sleep apnea-hypopnea syndrome (OSAHS) in children and influencing factors of enuresis with OSAHS.
METHODS
We recruited 196 children ≥5 years old from the otolaryngology outpatient department, who experienced snoring and underwent nasopharynx lateral radiography and in-laboratory polysomnography. We analyzed correlations between the apnea-hypopnea index (AHI) and lowest oxygen saturation (L-SaO2) with age, body mass index (BMI), tonsil size, and adenoidal-nasopharyngeal (A/N) ratio using the Pearson correlation test. Differences in severe OSAHS prevalence, age, AHI, L-SaO2, tonsil size, and A/N ratio between children with and without enuresis were assessed using the chi-square test and t-test. Risk factors of enuresis were analyzed using logistic regression. Follow-up was conducted to assess remission in children with enuresis after adenotonsillectomy.
RESULTS
BMI, tonsil size, and A/N ratio were correlated with AHI and L-SaO2. Severe OSAHS prevalence, AHI, tonsil size, and A/N ratio were higher and L-SaO2 were lower in children with enuresis. Logistic regression showed that BMI, AHI, tonsil size, and sleep apnea were risk factors for enuresis.
CONCLUSIONS
Our study findings showed that enuresis was associated with OSAHS in children. Adenotonsillectomy may improve the symptoms of enuresis.
目的
探讨儿童遗尿与阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的关系，以及 OSAHS 遗尿的影响因素。
方法
我们招募了 196 名 5 岁以上因打鼾而在耳鼻喉科门诊就诊并接受鼻咽侧位片和实验室多导睡眠图检查的儿童。我们分析了呼吸暂停低通气指数（AHI）和最低血氧饱和度（L-SaO2）与年龄、体重指数（BMI）、扁桃体大小、腺样体-鼻咽（A/N）比值之间的相关性，使用 Pearson 相关检验。使用卡方检验和 t 检验评估遗尿儿童与无遗尿儿童之间严重 OSAHS 患病率、年龄、AHI、L-SaO2、扁桃体大小和 A/N 比值的差异。使用逻辑回归分析遗尿的危险因素。对遗尿儿童行扁桃体腺样体切除术（adenotonsillectomy）后遗尿的缓解情况进行随访。
结果
BMI、扁桃体大小和 A/N 比值与 AHI 和 L-SaO2 相关。遗尿儿童的严重 OSAHS 患病率、AHI、扁桃体大小和 A/N 比值较高，L-SaO2 较低。Logistic 回归显示 BMI、AHI、扁桃体大小和睡眠呼吸暂停是遗尿的危险因素。
结论
我们的研究结果表明，遗尿与儿童 OSAHS 有关。扁桃体腺样体切除术可能改善遗尿症状。
Zotero 插件