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2010 年巴西里约热内卢尼泰罗伊市学童的出生体重、生命历程因素与超重。

Birth weight, life course factors and excess weight among schoolchildren in Niterói, Rio de Janeiro, Brazil in 2010.

机构信息

Universidade Federal do Rio de Janeiro (UFRJ), Instituto de Estudos em Saúde Coletiva (IESC), Rio de Janeiro, RJ, Brazil.

Universidade Federal do Rio de Janeiro (UFRJ), Instituto de Estudos em Saúde Coletiva (IESC), Rio de Janeiro, RJ, Brazil.

出版信息

J Pediatr (Rio J). 2021 Sep-Oct;97(5):531-539. doi: 10.1016/j.jped.2020.10.012. Epub 2020 Dec 6.

Abstract

OBJECTIVE

To investigate the association between birth weight and excess weight among students aged 6-14 years, adjusted for life course confounding factors.

METHODS

Cross-sectional study with 6-14-year-old schoolchildren in 2010; 795 school children from two public schools. In addition, a sub-sample was selected using a case-cohort study approach. Sociodemographic, breastfeeding, food introduction, previous weight gain, family history, current clinical and behavioral variables as well as maternal variables related to pregnancy, were collected. Multivariable weighted logistic regression was used to evaluate the association between birth weight and overweight. All prevalent cases of overweight (n = 160) were selected to compose the case group and a random sub-sample of all students participating in the study (n = 276 students, of whom 88 were cases) were the control group.

RESULTS

An unadjusted 6% increase in the excess weight prevalence ratio (p-value = 0.004) was found for each 100 g increase in birth weight. With adjustment for age, sex and behavioral variables (models 1 and 2), the association of birth weight with excess weight was positive and statistically significant, but it was no longer significant in the final model (model 3) when clinical variables were considered.

CONCLUSIONS

Although some of the secondary associations were statistically significant, we could not identify a significant association between birthweight and excess weight in adolescents.

摘要

目的

探究在校 6-14 岁学生的出生体重与超重之间的关系,并对其进行校正以排除生命历程混杂因素的影响。

方法

本研究为 2010 年进行的一项 6-14 岁在校儿童的横断面研究,共纳入来自两所公立学校的 795 名学生。此外,还采用病例-队列研究方法选择了一个子样本。收集了社会人口统计学、母乳喂养、食物引入、既往体重增加、家族史、当前临床和行为变量以及与妊娠相关的母亲变量。采用多变量加权逻辑回归来评估出生体重与超重之间的关系。所有超重的现患病例(n=160)被选入病例组,而所有参加研究的学生的随机子样本(n=276 名学生,其中 88 例为病例)被选入对照组。

结果

出生体重每增加 100g,超重的患病率比值(p 值=0.004)未经校正增加 6%。在校正年龄、性别和行为变量(模型 1 和 2)后,出生体重与超重之间存在正相关且具有统计学意义,但当考虑临床变量时,这种关联在最终模型(模型 3)中不再显著。

结论

尽管一些次要关联具有统计学意义,但我们无法在青少年中确定出生体重与超重之间存在显著关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4c3/9432005/f601fc251a2b/gr1.jpg

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