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为所有巴西亚马逊原住民地区提供抗蛇毒血清治疗:“每个生命都有同等价值”。

Providing Antivenom Treatment Access to All Brazilian Amazon Indigenous Areas: 'Every Life Has Equal Value'.

机构信息

Department of Medicine and Nursing, School of Health Sciences, Amazonas State University, Manaus 69065-001, Amazonas, Brazil.

Department of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69040-000, Amazonas, Brazil.

出版信息

Toxins (Basel). 2020 Dec 5;12(12):772. doi: 10.3390/toxins12120772.

DOI:10.3390/toxins12120772
PMID:33291444
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7762137/
Abstract

Snakebites are more frequent in the Brazilian Amazon than in other parts of Brazil, representing a high cost for the health system since antivenoms are only available through medical prescription from central municipal hospitals in most cases. The need for a cold chain and physicians usually restricts access to the only effective treatment of a snakebite, the antivenom. The complex topography of the rivers contributes to delays in treatment, and consequently increases the risk of severe complications, chronic sequelae and death. Thus, decentralization of antivenom treatment to primary healthcare facilities in the interior would increase access by indigenous population groups to proper healthcare. To standardize and evaluate the decentralization to low complexity indigenous healthcare units, we suggest the (i) development and validation of standardized operational procedures, (ii) training of professionals in the validated protocol in a referral health unit, (iii) implementation of the protocol in an indigenous healthcare unit, (iv) assessment of perceptions towards and acceptability of the protocol, and (v) estimation of the impact of the protocol's implementation. We expect that antivenom decentralization would shorten the time between diagnosis and treatment and, as such, improve the prognosis of snakebites. As health cosmology among indigenous populations has an important role in maintaining their way of life, the introduction of a new therapeutic strategy to their customs must take into account the beliefs of these peoples. Thus, antivenom administration would be inserted as a crucial therapeutic tool in a world of diverse social, natural and supernatural representations. The information presented here also serves as a basis to advocate for support and promotion of health policy initiatives focused on evidence-based care in snakebite management.

摘要

在巴西亚马逊地区,蛇咬伤比在巴西其他地区更为常见,这对医疗系统造成了高昂的成本,因为抗蛇毒血清通常只能通过中心市立医院的医疗处方获得。由于需要冷链和医生的参与,通常会限制获得唯一有效的蛇咬伤治疗方法——抗蛇毒血清。河流的复杂地形导致治疗延误,从而增加了严重并发症、慢性后遗症和死亡的风险。因此,将抗蛇毒血清治疗去中心化到内地的初级保健机构,将增加土著人群获得适当医疗保健的机会。为了标准化和评估向低复杂度的土著医疗单位的去中心化,我们建议:(i) 制定和验证标准化操作程序;(ii) 在转诊保健单位对专业人员进行经过验证的方案培训;(iii) 在土著医疗单位实施方案;(iv) 评估对方案的看法和可接受性;(v) 估计方案实施的影响。我们预计,抗蛇毒血清的去中心化将缩短从诊断到治疗的时间,从而改善蛇咬伤的预后。由于土著人群的健康宇宙观在维持其生活方式方面发挥着重要作用,因此,向他们的传统中引入新的治疗策略必须考虑到这些民族的信仰。因此,抗蛇毒血清的使用将作为一种关键的治疗工具,纳入到一个充满多样化社会、自然和超自然观念的世界中。这里介绍的信息也可以作为基础,倡导支持和推动以循证为基础的蛇伤管理为重点的卫生政策倡议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/1822ecde7ea7/toxins-12-00772-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/dd3a6fbf35a4/toxins-12-00772-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/0c92d09ffd8e/toxins-12-00772-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/c92578203ab6/toxins-12-00772-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/1822ecde7ea7/toxins-12-00772-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/dd3a6fbf35a4/toxins-12-00772-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/0c92d09ffd8e/toxins-12-00772-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/c92578203ab6/toxins-12-00772-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2d/7762137/1822ecde7ea7/toxins-12-00772-g004.jpg

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