Potential for and Other Bacterial Toxins as Biological Control Agents to Combat Dipteran Pests of Medical and Agronomic Importance.

The control of dipteran pests is highly relevant to humans due to their involvement in the transmission of serious diseases including malaria, dengue fever, Chikungunya, yellow fever, zika, and filariasis; as well as their agronomic impact on numerous crops. Many bacteria are able to produce proteins that are active against insect species. These bacteria include , the most widely-studied pesticidal bacterium, which synthesizes proteins that accumulate in crystals with insecticidal properties and which has been widely used in the biological control of insects from different orders, including Lepidoptera, Coleoptera, and Diptera. In this review, we summarize all the bacterial proteins, from and other entomopathogenic bacteria, which have described insecticidal activity against dipteran pests, including species of medical and agronomic importance.