Departamento de Agronomía, Biotecnología y Alimentación, Universidad Pública de Navarra, 31006 Pamplona, Spain.
Bioinsectis SL, Avda Pamplona 123, Mutilva, 31192 Navarra, Spain.
Toxins (Basel). 2020 Dec 5;12(12):773. doi: 10.3390/toxins12120773.
The control of dipteran pests is highly relevant to humans due to their involvement in the transmission of serious diseases including malaria, dengue fever, Chikungunya, yellow fever, zika, and filariasis; as well as their agronomic impact on numerous crops. Many bacteria are able to produce proteins that are active against insect species. These bacteria include , the most widely-studied pesticidal bacterium, which synthesizes proteins that accumulate in crystals with insecticidal properties and which has been widely used in the biological control of insects from different orders, including Lepidoptera, Coleoptera, and Diptera. In this review, we summarize all the bacterial proteins, from and other entomopathogenic bacteria, which have described insecticidal activity against dipteran pests, including species of medical and agronomic importance.
双翅目害虫的防治与人类息息相关，因为它们会传播疟疾、登革热、基孔肯雅热、黄热病、寨卡病毒和血丝虫病等严重疾病；此外，它们还会对许多农作物造成农艺影响。许多细菌能够产生对昆虫具有活性的蛋白质。这些细菌包括苏云金芽孢杆菌，这是研究最广泛的杀虫细菌，它合成的蛋白质在晶体中积累，具有杀虫特性，已被广泛用于不同目昆虫的生物防治，包括鳞翅目、鞘翅目和双翅目。在这篇综述中，我们总结了所有具有杀虫活性的细菌蛋白，包括苏云金芽孢杆菌和其他昆虫病原细菌，这些蛋白对双翅目害虫具有杀虫活性，包括具有医学和农艺重要性的物种。
