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扁桃体切除术后出血发生和时间的预测因素:病例对照研究。

Predictors of Occurrence and Timing of Post-Tonsillectomy Hemorrhage: A Case-Control Study.

机构信息

Department of Otolaryngology, Emory University School of Medicine, Atlanta, Georgia, USA.

Department of Otolaryngology, Washington University School of Medicine, Saint Louis, MO, USA.

出版信息

Ann Otol Rhinol Laryngol. 2021 Jul;130(7):825-832. doi: 10.1177/0003489420978010. Epub 2020 Dec 8.

Abstract

OBJECTIVE

To describe cases and timing of pediatric post-tonsillectomy hemorrhage (PTH), to evaluate predictors of PTH, and to determine the optimal amount of postoperative care unit (PACU) monitoring time.

STUDY DESIGN

Using the Pediatric Health Information System (PHIS) database and electronic medical records, a matched case-control study from 2005 to 2015 was performed.

SETTING

A single, tertiary-care institution.

SUBJECTS AND METHODS

Each case of PTH was matched with 1 to 4 controls for the following factors: age, sex, surgeon, and time of year. A total of 124 cases of PTH and 479 tonsillectomy controls were included. The rate and timing of postoperative bleeding were assessed, and matched pair analysis was performed using conditional logistic regression.

RESULTS

Our institutional PTH rate of 1.9% (130 of 6949) included 124 patients; 15% (19) were primary (≤24 hours), with 50% (9) occurring within 5 hours. Twenty-one percent (4 of 19) of primary PTH patients received operative intervention. Eighty-five percent (105 of 124) of all cases were secondary PTH, and 47% (49) of those patients received operative intervention. Cold steel (OR 1.9, 95% CI 1.1-3.3) and Coblation (OR 1.9, 95% CI 1.2-3.1) techniques and tonsillectomy alone (OR 3.7, 95% CI 1.9-7.2) increased odds of PTH. Patients who developed PTH had 4 times the odds of having a preceding postoperative respiratory event than controls (OR 4.0, 95% CI 1.6-10.0).

CONCLUSION

We conducted a rigorous case-control study for PTH, finding that PTH was associated with use of cold steel and Coblation techniques and with tonsillectomy alone. Patients with a postoperative respiratory event may be more likely to develop a PTH and should be counseled accordingly. A PACU monitoring time of 4 hours is sufficient for outpatient tonsillectomy.

摘要

目的

描述小儿扁桃体切除术后出血(PTH)的病例和时间,评估 PTH 的预测因素,并确定最佳的术后护理单元(PACU)监测时间。

研究设计

使用儿科健康信息系统(PHIS)数据库和电子病历,进行了一项 2005 年至 2015 年的匹配病例对照研究。

地点

单一的三级保健机构。

对象和方法

每例 PTH 病例均与 1 至 4 例对照病例进行匹配,匹配因素包括年龄、性别、外科医生和一年中的时间。共纳入 124 例 PTH 病例和 479 例扁桃体切除术对照病例。评估了术后出血的发生率和时间,并使用条件逻辑回归进行了匹配对分析。

结果

我院 PTH 发生率为 1.9%(6949 例中的 130 例),其中包括 124 例患者;15%(19 例)为原发性(≤24 小时),其中 50%(9 例)发生在 5 小时内。19 例原发性 PTH 患者中有 21%(4 例)接受了手术干预。所有病例中 85%(105 例)为继发性 PTH,其中 47%(49 例)患者接受了手术干预。冷钢(OR 1.9,95%CI 1.1-3.3)和等离子(OR 1.9,95%CI 1.2-3.1)技术以及单独行扁桃体切除术(OR 3.7,95%CI 1.9-7.2)增加了 PTH 的发生几率。与对照组相比,发生 PTH 的患者发生术后呼吸事件的几率增加了 4 倍(OR 4.0,95%CI 1.6-10.0)。

结论

我们进行了一项严格的 PTH 病例对照研究,发现 PTH 与使用冷钢和等离子技术以及单独行扁桃体切除术有关。术后发生呼吸事件的患者可能更容易发生 PTH,应相应地进行咨询。门诊扁桃体切除术的 PACU 监测时间 4 小时是足够的。

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