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成人扁桃体切除术后出血的评估及危险因素分析:来自佐治亚州一家国家耳鼻喉(ENT)中心的经验

Evaluation and Risk Factor Analysis of Post-tonsillectomy Hemorrhage in an Adult Population: An Experience From a National Ear, Nose, and Throat (ENT) Center in Georgia.

作者信息

Besiashvili Nino, Datikashvili-David Irina G, Gakharia Tatia

机构信息

School of Natural Sciences and Medicine, Ilia State University, Tbilisi, GEO.

Otolaryngology, National Center of Otorhinolaryngology, Japaridze-Kevanishvili Clinic, Tbilisi, GEO.

出版信息

Cureus. 2024 Sep 1;16(9):e68371. doi: 10.7759/cureus.68371. eCollection 2024 Sep.

Abstract

BACKGROUND

Tonsillectomy, a common surgical procedure for removing the palatine tonsils, is frequently performed in the otorhinolaryngology department. Tonsillectomy, with or without adenoidectomy, is considered a straightforward operation. However, serious complications, such as post-tonsillectomy hemorrhage, can complicate the recovery period. The research aims to analyze and estimate the factors associated with postoperative bleeding in the adult Georgian population.

METHOD

We conducted a cross-sectional study. The data was collected retrospectively from the medical records of adult patients aged 18 years and older, who underwent tonsillectomy in 2022 and 2023 at the National Center of Otorhinolaryngology, Japaridze-Kevanishvili Clinic, in Georgia. We performed univariate analysis using binary logistic regression and multivariate logistic regression analysis and calculated odds ratio (OR) to identify factors associated with postoperative bleeding among patients with tonsillectomy. A p-value of <0.05 was considered statistically significant.

RESULTS

A total of 778 adult patients with tonsillectomy were included in the study. Post-tonsillectomy hemorrhage occurred in 14.7% (n=114) of cases, with primary bleeding observed in 8.1% (n=63) of patients and secondary bleeding in 6.6% (n=51) of cases. The highest incidence of bleeding was observed on days 1 (8.1%, n=63) and 7 (1.3%, n=10). The statistical analysis revealed a statistically significant association between post-tonsillectomy hemorrhage and several factors: smoking status (OR=10.1, 95% CI: 6.1-16.7, p<0.001) and having a body mass index (BMI) greater than 25 (OR=3.6, 95% CI: 2.1-6.1, p<0.001).

CONCLUSION

The study confirmed several significant risk factors, including smoking and higher BMI, that are associated with an increased risk of bleeding among patients, undergoing tonsillectomy. Further research is needed to validate these findings in the Georgian population.

摘要

背景

扁桃体切除术是一种切除腭扁桃体的常见外科手术,在耳鼻喉科经常进行。扁桃体切除术,无论是否同时进行腺样体切除术,都被认为是一种简单的手术。然而,严重的并发症,如扁桃体切除术后出血,会使恢复期变得复杂。该研究旨在分析和评估格鲁吉亚成年人群中与术后出血相关的因素。

方法

我们进行了一项横断面研究。数据是从2022年和2023年在格鲁吉亚国家耳鼻喉科中心贾帕里泽 - 凯瓦尼什维利诊所接受扁桃体切除术的18岁及以上成年患者的病历中回顾性收集的。我们使用二元逻辑回归和多元逻辑回归分析进行单变量分析,并计算优势比(OR)以确定扁桃体切除术后患者中与术后出血相关的因素。p值<0.05被认为具有统计学意义。

结果

共有778名接受扁桃体切除术的成年患者纳入研究。扁桃体切除术后出血发生率为14.7%(n = 114),其中原发性出血见于8.1%(n = 63)的患者,继发性出血见于6.6%(n = 51)的病例。出血发生率最高的是第1天(8.1%,n = 63)和第7天(1.3%,n = 10)。统计分析显示扁桃体切除术后出血与几个因素之间存在统计学显著关联:吸烟状况(OR = 10.1,95% CI:6.1 - 16.7,p < 0.001)以及体重指数(BMI)大于25(OR = 3.6,95% CI:2.1 - 6.1,p < 0.001)。

结论

该研究证实了几个重要的风险因素,包括吸烟和较高的BMI,这些因素与接受扁桃体切除术的患者出血风险增加有关。需要进一步研究以在格鲁吉亚人群中验证这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff8d/11444841/c3cac4109432/cureus-0016-00000068371-i01.jpg

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