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心水病血清学：结果解读中的一些问题。

Heartwater serology: some problems with the interpretation of results.

作者信息

Du Plessis J L, Camus E, Oberem P T, Malan L

机构信息

Veterinary Research Institute, Onderstepoort.

出版信息

Onderstepoort J Vet Res. 1987 Sep;54(3):327-9.

PMID:3329323
Abstract

Antibodies in the sera of domestic ruminants that have been infected with Ehrlichia bovis and other ehrlichial agents cross-react with the Kümm strain of Cowdria ruminantium used in the indirect fluorescent antibody test as antigen. These cross-reactions are also shown by the Elisa test in which the Ball 3 strain of the heartwater agent is used as antigen.

摘要

感染了牛埃立克体及其他埃立克体病原体的家养反刍动物血清中的抗体，与间接荧光抗体试验中用作抗原的反刍动物考德里氏体库姆菌株发生交叉反应。以心水病病原体的鲍尔3菌株作为抗原的酶联免疫吸附测定试验也显示出这些交叉反应。

相似文献

1
Heartwater serology: some problems with the interpretation of results.心水病血清学：结果解读中的一些问题。
Onderstepoort J Vet Res. 1987 Sep;54(3):327-9.
2
The detection of antibodies cross-reacting with Cowdria ruminantium in the sera of domestic ruminants in regions of South Africa where Amblyomma hebraeum does not occur.
Onderstepoort J Vet Res. 1994 Dec;61(4):277-81.
3
Serotypes in Cowdria ruminantium and their relationship with Ehrlichia phagocytophila determined by immunofluorescence.
Vet Microbiol. 1989 Nov;21(1):31-40. doi: 10.1016/0378-1135(89)90016-3.
4
Increased pathogenicity of an Ehrlichia-like agent after passage through Amblyomma hebraeum: a preliminary report.
Onderstepoort J Vet Res. 1990 Dec;57(4):233-7.
5
[Comparison between 3 antigens for the serodiagnosis of heartwater disease by indirect immunofluorescence].
Rev Elev Med Vet Pays Trop. 1990;43(2):159-66.
6
The detection of antibodies to Cowdria ruminantium in serum and C. ruminantium antigen in Amblyomma hebraeum by an enzyme-linked immunosorbent assay.通过酶联免疫吸附测定法检测血清中反刍动物考德里氏体抗体以及希伯来花蜱中的反刍动物考德里氏体抗原。
Onderstepoort J Vet Res. 1986 Mar;53(1):39-41.
7
Susceptibility to heartwater of calves born to non-immune cows.未免疫母牛所产犊牛对心水病的易感性。
Onderstepoort J Vet Res. 1988 Dec;55(4):235-7.
8
The heterogenicity of Cowdria ruminantium stocks: cross-immunity and serology in sheep and pathogenicity to mice.反刍动物埃立克体菌株的异质性：绵羊的交叉免疫和血清学以及对小鼠的致病性
Onderstepoort J Vet Res. 1989 Sep;56(3):195-201.
9
Preliminary observations on the use of the capillary flocculation test for the diagnosis of heartwater (Cowdria ruminantium infection).关于使用毛细管絮凝试验诊断心水病（反刍兽考德里氏体感染）的初步观察
Res Vet Sci. 1976 Nov;21(3):370-2.
10
Development and evaluation of a recombinant antigen, monoclonal antibody-based competitive ELISA for heartwater serodiagnosis.用于心水病血清学诊断的基于重组抗原和单克隆抗体的竞争性酶联免疫吸附测定的开发与评估
J Vet Diagn Invest. 1997 Apr;9(2):130-5. doi: 10.1177/104063879700900204.

引用本文的文献

1
Development of a polyclonal competitive enzyme-linked immunosorbent assay for detection of antibodies to Ehrlichia ruminantium.用于检测反刍兽埃立克体抗体的多克隆竞争酶联免疫吸附测定法的开发。
Clin Diagn Lab Immunol. 2003 Sep;10(5):910-6. doi: 10.1128/cdli.10.5.910-916.2003.
2
Antibody responses to MAP 1B and other Cowdria ruminantium antigens are down regulated in cattle challenged with tick-transmitted heartwater.在受到蜱传播的牛心水病攻击的牛中，对微管相关蛋白1B（MAP 1B）和其他反刍动物考德里氏体抗原的抗体反应受到下调。
Clin Diagn Lab Immunol. 2001 Mar;8(2):388-96. doi: 10.1128/CDLI.8.2.388-396.2001.
3
Potential value of major antigenic protein 2 for serological diagnosis of heartwater and related ehrlichial infections.
主要抗原蛋白2在牛心水病及相关埃立克体感染血清学诊断中的潜在价值
Clin Diagn Lab Immunol. 1999 Mar;6(2):209-15. doi: 10.1128/CDLI.6.2.209-215.1999.
4
Evidence to show that an agent that cross-reacts serologically with Cowdria ruminantium in Zimbabwe is transmitted by ticks.有证据表明，在津巴布韦与反刍兽考德里氏体发生血清交叉反应的一种病原体是由蜱传播的。
Exp Appl Acarol. 1998 Feb;22(2):111-22. doi: 10.1023/a:1006045710683.
5
An immunoblotting diagnostic assay for heartwater based on the immunodominant 32-kilodalton protein of Cowdria ruminantium detects false positives in field sera.一种基于反刍动物考德里氏体免疫显性32千道尔顿蛋白的牛心水病免疫印迹诊断检测方法在现场血清中检测到假阳性。
J Clin Microbiol. 1993 Oct;31(10):2729-37. doi: 10.1128/jcm.31.10.2729-2737.1993.
6
Correlation between antibodies to Cowdria ruminantium (rickettsiales) in cattle and the distribution of Amblyomma vector ticks in Zimbabwe.津巴布韦牛体内反刍动物考德里氏体（立克次氏体目）抗体与钝缘蜱传播媒介蜱分布的相关性
Exp Appl Acarol. 1993 Nov;17(11):799-810. doi: 10.1007/BF00225853.
7
Use of a specific immunogenic region on the Cowdria ruminantium MAP1 protein in a serological assay.在血清学检测中使用反刍动物考德里氏体MAP1蛋白上的特定免疫原性区域。
J Clin Microbiol. 1995 Sep;33(9):2405-10. doi: 10.1128/jcm.33.9.2405-2410.1995.
8
Identification of an immunodominant antigenically conserved 32-kilodalton protein from Cowdria ruminantium.从反刍动物考德里氏体中鉴定出一种免疫显性的、抗原性保守的32千道尔顿蛋白。
Infect Immun. 1989 Oct;57(10):3243-6. doi: 10.1128/iai.57.10.3243-3246.1989.
9
Isolation of a previously undescribed rickettsia from an aborted bovine fetus.从一头流产的牛胎儿中分离出一种此前未被描述的立克次氏体。
J Clin Microbiol. 1990 Apr;28(4):814-6. doi: 10.1128/jcm.28.4.814-816.1990.