Cleaver Jonathan, James Richard, Rice Claire M
Department of Neurology, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.
Department of Neurology, North Bristol NHS Trust, Bristol, UK.
Pract Neurol. 2020 Dec 8. doi: 10.1136/practneurol-2020-002680.
Rhomboencephalitis-inflammation of the brainstem and cerebellum-has myriad clinical presentations including encephalopathy, cranial neuropathies, long tract signs and cerebellar dysfunction and is associated with significant morbidity and mortality. There are a variety of potential underlying causes that respond variably to treatment, including infections, parainfective syndromes, inflammatory disorders including autoimmune encephalitis and paraneoplastic syndromes. Here, we review its clinical presentation and outline a practical approach to its investigation, aiming to facilitate prompt diagnosis and confirmation of the underlying cause, to start appropriate management early and optimise the clinical outcome.
菱形脑炎（脑干和小脑的炎症）有多种临床表现，包括脑病、颅神经病变、长束征和小脑功能障碍，且与显著的发病率和死亡率相关。有多种潜在的潜在病因，对治疗的反应各不相同，包括感染、感染后综合征、炎症性疾病，包括自身免疫性脑炎和副肿瘤综合征。在此，我们回顾其临床表现，并概述一种实用的调查方法，旨在促进潜在病因的快速诊断和确认，尽早开始适当的管理并优化临床结果。
