Emory University School of Medicine, Department of Neurology, Atlanta, GA, United States of America.
Emory University School of Medicine, Department of Neurology, Atlanta, GA, United States of America.
J Neuroimmunol. 2021 Aug 15;357:577623. doi: 10.1016/j.jneuroim.2021.577623. Epub 2021 May 29.
A wide number of neurological manifestations have been described in association with coronavirus disease 19 (COVID-19). We describe an unusual case of a young man who developed severe rhombencephalitis after COVID-19. He demonstrated clinical and radiological improvement with high dose corticosteroids, plasma exchange and intravenous immune globulin. Our findings, along with previously reported cases that we review here, support an autoimmune para- or post-infectious mechanism and highlight a possible role for immunotherapy in patients with rhombencephalitis after COVID-19.
已描述了与 2019 年冠状病毒病(COVID-19)相关的大量神经表现。我们描述了一例不常见的年轻男性 COVID-19 后发生严重脑桥脑炎的病例。他接受大剂量皮质类固醇、血浆置换和静脉注射免疫球蛋白治疗后,临床和影像学均有改善。我们的发现以及我们在此处回顾的以前报道的病例支持自身免疫性副感染或感染后机制,并强调免疫疗法在 COVID-19 后脑桥炎患者中的可能作用。