Sarvazad H, Cahngaripour S H, Eskandari Roozbahani N, Izadi B
Clinical Research Development Centre, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Molecular Pathology Research Centre, Imam Reza Hospital, Kermanshah University of Medical Science, Zakaria Razi Blv, Kermanshah, Iran.
New Microbes New Infect. 2020 Nov 7;38:100807. doi: 10.1016/j.nmni.2020.100807. eCollection 2020 Nov.
We examined electrolyte imbalance and blood sugar levels in patients with COVID-19 who had no underlying disease. This cross-sectional study in a clinical center was performed in Kermanshah, west of Iran. All patients who had a record of magnesium (Mg), potassium (K), sodium (Na+), and fasting blood sugar (FBS) tests in their clinical files at the time of admission to the hospital from April 21 to July 12, and didn't have a history of an underlying disease, were included in the study. Patients were divided into outpatient (as less severe COVID-19) and intensive care units (ICU) (as severe COVID-19). For statistical analysis of collected data, the SPSS software (version 16) was used. Among a total of 134 patients, 58 cases (24 ICU and 34 outpatients) were included in the study. The mean and median age was 56 and 62 years, respectively. From all included, 33 men (57%), 25 women (43%), 52 urban (89.7%), 6 rural (10.3%), 41 alive (70.7%), and 17 died (29.3%) were recorded. From all included patients, 49.1% hyperglycemia, 38% hyponatremia, 7.3% hypokalemia, and 32% hypomagnesemia were observed. Unlike the mean of age and the level of K+, there was a statistically significant difference between the outpatient and ICU groups in terms of Mg, Na, and FBS (p < 0.05). Hyperglycemia and electrolyte imbalance in COVID-19 patients is feasible. Therefore, notice to measuring these cases and monitoring the patient can be effective in the treatment process and prevent the serious complications of the disease.
我们对无基础疾病的新冠肺炎患者的电解质失衡和血糖水平进行了检查。这项在伊朗西部克尔曼沙赫一家临床中心开展的横断面研究。纳入了所有在4月21日至7月12日入院时临床档案中有镁(Mg)、钾(K)、钠(Na+)和空腹血糖(FBS)检测记录且无基础疾病史的患者。患者被分为门诊患者(新冠肺炎病情较轻者)和重症监护病房(ICU)患者(新冠肺炎病情严重者)。对于收集到的数据进行统计分析时,使用了SPSS软件(版本16)。在总共134名患者中,有58例(24例ICU患者和34例门诊患者)被纳入研究。平均年龄和年龄中位数分别为56岁和62岁。在所有纳入患者中,记录到33名男性(57%)、25名女性(43%)、52名城市居民(89.7%)、6名农村居民(10.3%)、41名存活患者(70.7%)以及17名死亡患者(29.3%)。在所有纳入患者中,观察到49.1%的患者血糖升高、38%的患者低钠血症、7.3%的患者低钾血症以及32%的患者低镁血症。与年龄均值和钾离子水平不同,门诊患者组和ICU患者组在镁、钠和空腹血糖方面存在统计学显著差异(p<0.05)。新冠肺炎患者出现血糖升高和电解质失衡是可能的。因此,注意检测这些情况并对患者进行监测在治疗过程中可能有效,并可预防该疾病的严重并发症。