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干细胞:心血管疾病治疗的新方法。

Stem cells: a new way of therapy for cardiovascular disorders.

作者信息

Amjad Rabia, Ishtiaq Isha, Fatima Noor

机构信息

Department of Biotechnology, University of Sialkot, Sialkot, Pakistan.

出版信息

Stem Cell Investig. 2020 Nov 3;7:19. doi: 10.21037/sci-2019-048. eCollection 2020.

Abstract

Cardiovascular disorder affects the overall health of an individual and hence the quality of life. Stem cell therapy involves the use of stem cells widely used to treat different conditions. People having severe cardiovascular disorder can be treated with stem cells by generating heart muscles, stimulating the growth of blood vessels and by the secretion of different growth factors. Different types of stem cells are used for cardiac repair. Adipose stem cells and induced pluripotent stem cells are better options for increasing the survival rate. In this review we will discuss different types of stem cells, their activation pathway, generation, hurdles in transplantation and how to overcome them and their applications.

摘要

心血管疾病会影响个人的整体健康,进而影响生活质量。干细胞疗法涉及使用干细胞,干细胞被广泛用于治疗各种病症。患有严重心血管疾病的人可以通过生成心肌、刺激血管生长以及分泌不同的生长因子来用干细胞进行治疗。不同类型的干细胞用于心脏修复。脂肪干细胞和诱导多能干细胞是提高存活率的更好选择。在这篇综述中,我们将讨论不同类型的干细胞、它们的激活途径、生成、移植中的障碍以及如何克服这些障碍及其应用。

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