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一例具有胃分化的阴道腺病。

A case of vaginal adenosis with gastric differentiation.

作者信息

Awosogba Temitope P, Whitney Janelle, Broder Jennifer C, McKee Andrea, Paquette Cherie, Nitschmann Caroline C

机构信息

Department of Obstetrics and Gynecology, New York University Langone Health, 660 First Ave, New York, NY, 10016, USA.

Department of Obstetrics and Gynecology, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA.

出版信息

Gynecol Oncol Rep. 2020 Nov 6;34:100672. doi: 10.1016/j.gore.2020.100672. eCollection 2020 Nov.

DOI:10.1016/j.gore.2020.100672
PMID:33294576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7691171/
Abstract

•Vaginal adenosis is a non-obligate pre-cursor for vaginal clear cell carcinoma.•Vaginal adenosis is rare and presents with a variety of signs and symptoms.•Unclear link between adenosis and carcinoma without diethylstilbestrol exposure.•Surveillance with physical examinations, imaging and biopsies is recommended.

摘要

•阴道腺病是阴道透明细胞癌的非必要前驱病变。

•阴道腺病罕见，表现为多种体征和症状。

•无己烯雌酚暴露情况下，腺病与癌之间的联系尚不明确。

•建议通过体格检查、影像学检查和活检进行监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/64e14f62e8cd/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/beec500f45c2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/0cbcb2347724/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/43b2fd01a685/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/64e14f62e8cd/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/beec500f45c2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/0cbcb2347724/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/43b2fd01a685/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4887/7691171/64e14f62e8cd/gr4.jpg

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1
A case of vaginal adenosis with gastric differentiation.一例具有胃分化的阴道腺病。
Gynecol Oncol Rep. 2020 Nov 6;34:100672. doi: 10.1016/j.gore.2020.100672. eCollection 2020 Nov.
2
Malignant transformation of vaginal adenosis to clear cell carcinoma without prenatal diethylstilbestrol exposure: a case report and literature review.阴道腺病恶变为透明细胞癌，无产前己烯雌酚暴露：病例报告及文献复习。
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Primary Vaginal Gastric-type Adenocarcinoma and Vaginal Adenosis Exhibiting Gastric Differentiation: Report of a Series With Detailed Immunohistochemical Analysis.原发性阴道胃型腺癌和阴道腺病伴胃分化：一系列详细免疫组化分析的报道。
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Vaginal adenosis and adenocarcinoma in mice exposed prenatally or neonatally to diethylstilbestrol.在出生前或出生后接触己烯雌酚的小鼠中的阴道腺病和腺癌。
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[Endocervical form of the vaginal adenosis (author's transl)].阴道腺病的宫颈内膜型（作者译）
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本文引用的文献

1
Clinicopathologic features and outcomes of primary vaginal adenosis as a dermatologic and gynecologic burden: A retrospective study.原发性阴道腺病作为一种皮肤和妇科负担的临床病理特征及转归：一项回顾性研究
Medicine (Baltimore). 2018 Dec;97(49):e13470. doi: 10.1097/MD.0000000000013470.
2
Primary Vaginal Gastric-type Adenocarcinoma and Vaginal Adenosis Exhibiting Gastric Differentiation: Report of a Series With Detailed Immunohistochemical Analysis.原发性阴道胃型腺癌和阴道腺病伴胃分化：一系列详细免疫组化分析的报道。
Am J Surg Pathol. 2018 Jul;42(7):958-970. doi: 10.1097/PAS.0000000000001068.
3
Vaginal adenosis as a dermatologic complaint.
作为一种皮肤病主诉的阴道腺病。
J Am Acad Dermatol. 2013 Aug;69(2):e92-3. doi: 10.1016/j.jaad.2009.11.590.
4
The development of cervical and vaginal adenosis as a result of diethylstilbestrol exposure in utero.子宫内暴露于己烯雌酚会导致宫颈和阴道腺病的发展。
Differentiation. 2012 Oct;84(3):252-60. doi: 10.1016/j.diff.2012.05.004. Epub 2012 Jun 6.
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Vulval and vaginal adenosis.外阴及阴道腺病
Br J Dermatol. 1998 Jul;139(1):128-31. doi: 10.1046/j.1365-2133.1998.02329.x.
6
Maturation of vaginal and cervical epithelium in women exposed in utero to diethylstilbestrol (DESAD Project).子宫内暴露于己烯雌酚的女性阴道和宫颈上皮的成熟（DESAD项目）
Am J Obstet Gynecol. 1983 Jun 1;146(3):279-85. doi: 10.1016/0002-9378(83)90749-4.