Richard A and Susan F Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Department of Cardiovascular Medicine, Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.
Vasc Med. 2021 Jun;26(3):317-325. doi: 10.1177/1358863X20977016. Epub 2020 Dec 9.
Peripheral artery disease (PAD) is a progressive atherosclerotic disease associated with high rates of morbidity and mortality. Symptomatic PAD typically presents with claudication, and symptom severity strongly associates with reduced health-related quality of life (HRQoL). Existing treatment strategies for PAD are aimed at reducing symptom severity and improving functional outcomes. However, there is a need to incorporate patient-reported outcome measures (PROMs) into PAD treatment and research in order to provide more patient-centered care. This review will discuss the impact of PAD on HRQoL, existing PROMs available to assess PAD-related HRQoL, utilization of PROMs in research studies and registries, and challenges and solutions related to the integration of PROMs into research and clinical settings.
外周动脉疾病（PAD）是一种与高发病率和死亡率相关的进行性动脉粥样硬化疾病。有症状的 PAD 通常表现为跛行，症状严重程度与健康相关生活质量（HRQoL）降低密切相关。现有的 PAD 治疗策略旨在减轻症状严重程度并改善功能结局。然而，需要将患者报告的结果测量（PROMs）纳入 PAD 的治疗和研究中，以提供更以患者为中心的护理。这篇综述将讨论 PAD 对 HRQoL 的影响、现有的用于评估 PAD 相关 HRQoL 的 PROMs、PROMs 在研究和注册研究中的应用、以及将 PROMs 整合到研究和临床环境中相关的挑战和解决方案。
