Thompson M P, Grigor M R
Department of Biochemistry, University of Otago, Dunedin, New Zealand.
Biosci Rep. 1987 Nov;7(11):871-9. doi: 10.1007/BF01119478.
A significant diurnal variation in the rates of lipogenesis in vivo in brown adipose tissue occurred in both virgin and lactating rats. On a meal-feeding regime of either a chow, high-sucrose, or high-lipid diet, there was a very large increase in BAT lipogenesis following the meal. The rates observed after the sucrose meal are the highest so far reported. There was no significant difference in BAT lipogenesis between lactating and virgin rats, contrary to previous reports by others. The pattern of stimulation of BAT lipogenesis by these feeding regimes was different from that for white adipose tissue and liver and was not correlated with plasma insulin levels.
在未生育和哺乳期大鼠体内，棕色脂肪组织的脂肪生成速率均存在显著的昼夜变化。在喂食普通饲料、高蔗糖或高脂饮食的情况下，进食后棕色脂肪组织的脂肪生成大幅增加。蔗糖餐后观察到的速率是迄今为止报道的最高值。与其他人之前的报道相反，哺乳期大鼠和未生育大鼠的棕色脂肪组织脂肪生成没有显著差异。这些喂养方式对棕色脂肪组织脂肪生成的刺激模式不同于白色脂肪组织和肝脏，且与血浆胰岛素水平无关。
