Najafi Farid, Shadmani Fatemeh Khosravi, Ghalandari Mojtaba, Darbandi Mitra
Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Cardiovascular Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Arch Public Health. 2020 Dec 9;78(1):130. doi: 10.1186/s13690-020-00511-1.
The Middle East and North Africa, is one of few regions where the number of new human immunodeficiency virus infections is increasing. The present study aimed to estimate the attributable burden of unsafe sex and drug use in Acquired immunodeficiency syndrome in the Middle East and North Africa countries.
We used the Global Burden of Disease data 2017 to estimate the attributable mortality and disability-adjusted life-years to unsafe sex and drug use in Acquired immunodeficiency syndrome in the Middle East and North Africa countries (21 countries) from 1990 to 2017 by region, sex and age. The percent change was calculated at three time points by country and sex.
The rate of Disability-adjusted life years/100,000 attributed to drug use for Acquired immunodeficiency syndrome increased 1.10 (95% CI: 0.75-1.71) to 13.39 (95% CI: 9.98-18.17) in women of Middle East and North Africa countries from 1990 to 2017, and there is an increasing trend in Disability-adjusted life years attributable to drug use for Acquired immunodeficiency syndrome in men. The rate of Disability-adjusted life years/100,000 attributed to unsafe sex for Acquired immunodeficiency syndrome increased in women of Middle East and North Africa countries, 5.15 (95% CI: 3.34-8.07) to 53.44 (95% CI: 38.79-75.89); and 10.06 (95% CI: 6.61-16.18) to 46.16 (95% CI: 31.30-72.66) in men. Age-standardized mortality rate attributed to drug use and unsafe sex for Acquired immunodeficiency syndrome increased from 1990 to 2017 in both sex in Middle East and North Africa countries.
The rate of Disability-adjusted life years /100,000 and age-standardized mortality rate attributed to unsafe sex and drug use increased in Middle East and North Africa from 1990 to 2017. While most of such countries have traditional cultures with religious believes, such increase need to be addressed in more depth by all policy makers.
中东和北非是少数几个新的人类免疫缺陷病毒感染病例数正在增加的地区之一。本研究旨在估计中东和北非国家中不安全性行为和药物使用在获得性免疫缺陷综合征中所占的可归因负担。
我们使用2017年全球疾病负担数据，按地区、性别和年龄估算1990年至2017年中东和北非国家（21个国家）中不安全性行为和药物使用在获得性免疫缺陷综合征中导致的可归因死亡率和伤残调整生命年。按国家和性别在三个时间点计算百分比变化。
1990年至2017年，中东和北非国家女性中因药物使用导致的每10万人伤残调整生命年率从1.10（95%置信区间：0.75 - 1.71）增至13.39（95%置信区间：9.98 - 18.17），男性中因药物使用导致的获得性免疫缺陷综合征伤残调整生命年呈上升趋势。中东和北非国家女性中因不安全性行为导致的每10万人伤残调整生命年率从5.15（95%置信区间：3.34 - 8.07）增至53.44（95%置信区间：38.79 - 75.89）；男性从10.06（95%置信区间：6.61 - 16.18）增至46.16（95%置信区间：31.30 - 72.66）。1990年至2017年，中东和北非国家两性中因药物使用及不安全性行为导致的年龄标准化死亡率均上升。
1990年至2017年，中东和北非地区因不安全性行为和药物使用导致的每10万人伤残调整生命年率及年龄标准化死亡率上升。虽然这些国家大多有带有宗教信仰的传统文化，但所有政策制定者都需要更深入地应对这种增长。
