Department of Surgical Oncology and Endocrine Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Am J Surg. 2021 Aug;222(2):297-304. doi: 10.1016/j.amjsurg.2020.12.003. Epub 2020 Dec 3.
Decrease in blood pressure (BP) is the major goal of adrenalectomy for primary aldosteronism. Nevertheless, the optimal timing to assess these outcomes and the needed duration of follow-up are uncertain. We systematically reviewed the literature regarding trends in BP-related outcomes during follow-up after adrenalectomy.
A systematic literature search of medical literature from PubMed, Embase and the Cochrane Library regarding BP-related outcomes (i.e. cure of hypertension rates, BP and antihypertensives) was performed. The Quality In Prognosis Studies risk of bias tool was used.
Of the 2057 identified records, 13 articles met the inclusion criteria. Overall study quality was low. In multiple studies, the biggest decrease in BP was shown within the first month(s) after adrenalectomy and afterwards BP often remained stable during long-term follow-up.
Based on the available studies one might suggest that long follow-up is unnecessary, since outcomes seem to stabilize within the first months.
降低血压（BP）是原发性醛固酮增多症患者肾上腺切除术的主要目标。然而，评估这些结果的最佳时机和所需的随访时间尚不确定。我们系统地回顾了有关肾上腺切除术后随访期间与血压相关结果的文献趋势。
对来自 PubMed、Embase 和 Cochrane 图书馆的医学文献进行了系统的文献检索，以了解与血压相关的结果（即高血压治愈率、血压和抗高血压药物）。使用预后研究质量工具（Quality In Prognosis Studies）评估风险偏倚。
在 2057 条记录中，有 13 篇文章符合纳入标准。总体研究质量较低。在多项研究中，术后第一个月（或几个月）内血压下降最大，之后在长期随访中血压通常保持稳定。
根据现有研究，我们可以认为，长期随访是不必要的，因为结果似乎在最初几个月内就趋于稳定。
