炎症反应：肥胖导致抑郁的关键病理生理机制
Inflammatory Response, a Key Pathophysiological Mechanism of Obesity-Induced Depression.
机构信息
Department of Neuroscience, Institute for Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.
Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
出版信息
Mediators Inflamm. 2020 Nov 24;2020:8893892. doi: 10.1155/2020/8893892. eCollection 2020.
Abstract
In recent years, with the acceleration of life rhythm and the increase of social competition, the incidence of obesity and depression has been increasing, which has seriously affected the quality of life and health of people. Obesity and depression, two seemingly unrelated physical and psychological diseases, in fact, are closely related: obese people are more likely to have depression than nonobese ones. We have reviewed and analyzed the relevant research literature and found that the inflammatory response plays a key role in obesity-induced depression. This article will discuss in detail the inflammatory mechanisms by which obesity induces depression.
摘要
近年来，随着生活节奏的加快和社会竞争的加剧，肥胖和抑郁的发病率不断上升，严重影响了人们的生活质量和健康。肥胖和抑郁，两种看似无关的身心疾病，实际上却密切相关：肥胖者比非肥胖者更容易患上抑郁症。我们查阅和分析了相关的研究文献，发现炎症反应在肥胖导致的抑郁中起着关键作用。本文将详细讨论肥胖导致抑郁的炎症机制。
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