Sekiguchi Naoko, Nakashima Shinsuke, Koh Masahiro, Ueda Masami, Tsuda Yujiro, Tanida Tsukasa, Matsuyama Jin, Ikenaga Masakazu, Yamada Terumasa
Department of Surgery, Higashiosaka City Medical Center, Nishiiwata 3-4-5, Higashiosaka, Osaka, 567-8588, Japan.
Ann Med Surg (Lond). 2020 Nov 22;60:566-570. doi: 10.1016/j.amsu.2020.11.052. eCollection 2020 Dec.
Typically, SCN is single and doesn't invade around tissue. In our case, tumors were multiple and had gradually grown and caused vein stenosis. This is extremely rare and unique resected multiple SCN case. In addition, I report that it was thought to be educational that even benign tumors could cause such changes.
A 60-year-old female was diagnosed with 3 multilocular cystic tumors in distal pancreas by contrast enhanced computed tomography (CT) at the preoperative staging for rectal neoplasm. The diameters of cystic tumors were 22/23/29 mm. The CT showed that the tumors had multiple internal septa enhanced in the arterial phase and the second tumor contained internal calcifications located centrally. The main pancreatic duct was not dilated. Although SCN often occurred single and multiple SCN was very rare, we diagnosed that the tumors were suspected microcystic type SCN because they had typical image findings. So, we planned to follow up every six months after resection for rectal neoplasm. 2 years and half later, they had gradually grown, and splenic vein stenosis appeared. The pancreatic parenchyma atrophy and dilatation of the main pancreatic duct had been gradually progressing. We performed distal pancreatectomy because of possibility of malignancy. The histopathological findings showed that 2 cystic tumors the side of pancreatic head had a connection and had typical findings of SCA of pancreas. The other tumor was independent from two tumors. They had no malignant findings.
At first, we expected tumor invasion had caused the changes. But tumors had no malignant findings, so we considered that compression from the tumor had caused stenosis, and obstructive pancreatitis had induced the pancreatic parenchyma atrophy.
We learned from this case that not only invasion but also compression caused vein stenosis and pancreatic duct dilation.
通常,浆液性囊性肿瘤(SCN)是单发的,不会侵犯周围组织。在我们的病例中,肿瘤是多发的,并且逐渐生长并导致静脉狭窄。这是极为罕见且独特的切除多发SCN病例。此外,我报告认为,即使是良性肿瘤也可能导致此类变化,这具有一定的教育意义。
一名60岁女性在直肠肿瘤术前分期的对比增强计算机断层扫描(CT)中被诊断出胰腺远端有3个多房性囊性肿瘤。囊性肿瘤的直径分别为22/23/29毫米。CT显示肿瘤在动脉期有多个内部间隔增强,第二个肿瘤中央有内部钙化。主胰管未扩张。尽管SCN通常为单发,多发SCN非常罕见,但由于这些肿瘤具有典型的影像表现,我们诊断为疑似微囊性型SCN。因此,我们计划在直肠肿瘤切除术后每六个月进行一次随访。两年半后,肿瘤逐渐生长,出现脾静脉狭窄。胰腺实质萎缩和主胰管扩张也在逐渐进展。由于存在恶变可能性,我们进行了远端胰腺切除术。组织病理学检查结果显示,胰头侧的2个囊性肿瘤相连,具有胰腺浆液性囊腺瘤(SCA)的典型表现。另一个肿瘤与这两个肿瘤独立。它们没有恶性表现。
起初,我们认为是肿瘤侵犯导致了这些变化。但肿瘤没有恶性表现,所以我们认为是肿瘤的压迫导致了狭窄,并且梗阻性胰腺炎导致了胰腺实质萎缩。
我们从这个病例中学到,不仅侵犯,而且压迫也会导致静脉狭窄和胰管扩张。