Lukas Rimas V, Taylor Jennie W, Kurz Sylvia C, Mohile Nimish A
Department of Neurology (RVL), Northwestern University, Chicago, IL; The Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center (RVL), Chicago, IL; Departments of Neurology and Neurological Surgery (JWT), University of California-San Francisco; Department of Neurology (SCK), New York University, New York; Brain and Spine Tumor Center at the Perlmutter Cancer Center (SCK), New York, NY; and Department of Neurology (NAM), University of Rochester, NY.
Neurol Clin Pract. 2020 Oct;10(5):458-465. doi: 10.1212/CPJ.0000000000000765.
Neuro-oncologic patients are routinely encountered in clinical practice. Neuro-oncology is a rapidly evolving field, so understanding the most classic paradigms and contemporary advances will optimize patient care.
We discuss the recent reclassification of tumors via molecular characteristics as it applies to direct clinical practice and review the contemporary standard of care for infiltrating gliomas, meningiomas, brain metastases, and CNS lymphoma.
We provide a straightforward primer on neuro-oncology with a focus on the brain tumors most commonly encountered by the adult neurologist and a clear emphasis on clinically relevant points including those which have recently become incorporated into our standard management. We cite key reviews to allow interested readers an opportunity to gain a more comprehensive understanding of specific topics.
神经肿瘤患者在临床实践中很常见。神经肿瘤学是一个快速发展的领域,因此了解最经典的模式和当代进展将优化患者护理。
我们讨论了基于分子特征的肿瘤重新分类在直接临床实践中的应用,并回顾了浸润性胶质瘤、脑膜瘤、脑转移瘤和中枢神经系统淋巴瘤的当代护理标准。
我们提供了一份关于神经肿瘤学的简明入门指南,重点关注成年神经科医生最常遇到的脑肿瘤,并明确强调临床相关要点,包括那些最近已纳入我们标准治疗的要点。我们引用关键综述,以便有兴趣的读者有机会更全面地了解特定主题。