Franklin and Marshall College Department of Chemistry, Lancaster, Pennsylvania, USA.
Wabash College Department of Chemistry, Crawfordsville, Indiana, USA.
Biochem Mol Biol Educ. 2021 Jan;49(1):26-28. doi: 10.1002/bmb.21480. Epub 2020 Dec 10.
Colleges and universities are learning to provide relevant virtual lab experiences for students due to the COVID-19 pandemic. Even schools attempting in-person instruction often need to utilize virtual experiences for students absent due to quarantine or illness. Much of biochemistry is amenable to molecular visualization and/or computational study; however, many faculty face learning how to utilize new computational and molecular visualization software. We present a set of virtual lab exercises with detailed instructions to engage students in the discovery of novel antiviral compounds against the SARS-CoV-2 main protease.
由于 COVID-19 大流行,高校正在学习为学生提供相关的虚拟实验室体验。即使是采用面授教学的学校,也常常需要为因隔离或患病而缺勤的学生提供虚拟体验。生物化学的很大一部分内容适合进行分子可视化和/或计算研究;然而,许多教师需要学习如何使用新的计算和分子可视化软件。我们提供了一组带有详细说明的虚拟实验室练习,以激发学生发现针对 SARS-CoV-2 主蛋白酶的新型抗病毒化合物。