2-Hydroxynaphthalene based acylhydrazone as a turn-on fluorescent chemosensor for Al detection and its real sample applications.

Developing high performance fluorescent chemosensor for Al detection is highly desirable, due to the excess of Al will lead to many diseases. In this paper, a simple 2-hydroxynaphthalene-based fluorescent chemosensor has been synthesized and characterized by different spectroscopic methods. The compound exhibited an "turn-on-type" fluorescent chemosensing for the detection of Al, which was ascribed to the chelation-enhanced fluorescence (CHEF). The high selectivity and sensitivity of the compound for Al were verified by fluorescence spectra in its DMF solution, and the enhancement of fluorescent intensity could be observed by naked-eye from non-fluorescence to green light. The detection limit of the compound for Al was found to be 4.22 × 10 M and the stability constant was 4.82 × 10 M. The 1:1 binding stoichiometry of the compound to Al was confirmed from the Job's plot based on fluorescence titrations. Additionally, the sensing process of the compound to Al was chemically reversible by adding NaEDTA. Importantly, the probe was successfully applied to quantitative analysis of Al in real drug and potable water samples.