Kimura Sachi, Komura Tomozo, Yamaoka Naoto, Oka Hisashi
OAT Agrio, Regulatory Group, Research and Development Division.
Faculty of Agriculture, Ehime University.
J Pestic Sci. 2020 Nov 20;45(4):206-215. doi: 10.1584/jpestics.D19-076.
Flutianil, chemically characterized as a cyano-methylene thiazolidine, showed antifungal activity against powdery mildew on various crops but not any other plant pathogens tested. Flutianil showed high residual and translaminar activities and rainfastness against . It also exhibited curative activity against on cucumber at an extremely low concentration of 10 mg/L. There was no cross-resistance between flutianil and other existing fungicides. Morphological studies revealed that flutianil did not inhibit the early infection behavior of f. sp. , conidium bursting, primary and appressorial germinations, appressorium development and hook formations, but it did inhibit haustorium formation and further fungal development. Nutrient absorption by haustoria and subsequent secondary hyphal elongation was inhibited by flutianil but not by the fungicide that showed a similar inhibitory pattern up to the haustorium formation stage of the infection process. These findings suggest that flutianil might have a novel mode of action.
氟噻唑吡乙酮，化学上为氰基亚甲基噻唑烷，对多种作物上的白粉病表现出抗真菌活性，但对测试的其他植物病原体无活性。氟噻唑吡乙酮表现出高残留活性、跨层活性和耐雨水冲刷性。它在极低浓度10毫克/升时对黄瓜上的[病害名称未明确]也表现出治疗活性。氟噻唑吡乙酮与其他现有杀菌剂之间不存在交叉抗性。形态学研究表明，氟噻唑吡乙酮不抑制[病原菌名称未明确]f. sp. [具体种名未明确]的早期侵染行为、分生孢子破裂、初生和附着胞萌发、附着胞发育及附着胞钩形成，但它确实抑制吸器形成和真菌的进一步发育。氟噻唑吡乙酮抑制吸器对养分的吸收以及随后次生菌丝的伸长，而在侵染过程的吸器形成阶段之前表现出类似抑制模式的杀菌剂则无此作用。这些发现表明氟噻唑吡乙酮可能具有一种新的作用模式。
