Khurana Sandhya, Bush Andrew, Holguin Fernando
University of Rochester School of Medicine and Dentistry, Pulmonary and Critical Care Medicine, Rochester, NY, USA.
Dept of Paediatrics, National Heart & Lung Institute, Imperial College London, London, UK.
Breathe (Sheff). 2020 Jun;16(2):200058. doi: 10.1183/20734735.0058-2020.
This article is mainly intended for trainees and specialists who are interested in the management of severe asthma. It aims to inform readers about the updated ERS/ATS recommendations for management of severe asthma, specifically on the topics of biologics, macrolides and long-acting muscarinic antagonists.It also provides guidance on utilisation of available biomarkers in selecting advanced therapies in severe asthma.
本文主要面向对重度哮喘管理感兴趣的学员和专家。其目的是让读者了解欧洲呼吸学会(ERS)/美国胸科学会(ATS)关于重度哮喘管理的最新建议,特别是关于生物制剂、大环内酯类药物和长效毒蕈碱拮抗剂的主题。它还为在重度哮喘中选择先进疗法时利用可用生物标志物提供指导。