Sisson J C, Wieland D M
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109.
Am J Physiol Imaging. 1986;1(2):96-103.
Much was known of the pharmacology of meta-iodobenzylguanidine (MIBG) before its clinical use, but we have since learned a good deal more about the metabolic distribution and fate of this radiopharmaceutical. And, as is the nature of science, more is yet to be discovered. This communication reviews what is known about the pharmacology of radiolabeled MIBG and how this pharmacology affects the clinical studies that use the agent.
在间碘苄胍（MIBG）临床应用之前，人们就已经对其药理学有了很多了解，但自那时起，我们对这种放射性药物的代谢分布和归宿又有了更多认识。而且，正如科学的本质那样，还有更多有待发现。本文综述了关于放射性标记MIBG药理学的已知情况，以及这种药理学如何影响使用该药物的临床研究。
