Physical Medicine and Rehabilitation Clinic, University of Health Sciences, Bakırkoy Dr. Sadi Konuk Training Hospital, Istanbul, Turkey.
Rheumatology Division, Department of Medicine, Geneva University Hospital (HUG), Geneva, Switzerland.
Front Cell Infect Microbiol. 2020 Nov 10;10:491160. doi: 10.3389/fcimb.2020.491160. eCollection 2020.
Rheumatoid arthritis and spondyloarthropathy are the most common inflammatory rheumatic diseases. As the human microbiome is involved in the immune homeostasis, it has the potential to be a key factor in the development of autoimmune diseases and rheumatic diseases. In this article, we review the role of various human microbiota on the pathogenesis of rheumatic diseases, focusing on spondylarthritis and rheumatoid arthritis.
类风湿关节炎和脊柱关节炎是最常见的炎症性风湿病。由于人类微生物组参与免疫稳态,因此它有可能成为自身免疫性疾病和风湿病发展的关键因素。在本文中,我们综述了各种人类微生物组在风湿病发病机制中的作用,重点关注脊柱关节炎和类风湿关节炎。