综述：人类微生物组与风湿性疾病。
Mini-Review: Human Microbiome and Rheumatic Diseases.
机构信息
Physical Medicine and Rehabilitation Clinic, University of Health Sciences, Bakırkoy Dr. Sadi Konuk Training Hospital, Istanbul, Turkey.
Rheumatology Division, Department of Medicine, Geneva University Hospital (HUG), Geneva, Switzerland.
出版信息
Front Cell Infect Microbiol. 2020 Nov 10;10:491160. doi: 10.3389/fcimb.2020.491160. eCollection 2020.
Abstract
Rheumatoid arthritis and spondyloarthropathy are the most common inflammatory rheumatic diseases. As the human microbiome is involved in the immune homeostasis, it has the potential to be a key factor in the development of autoimmune diseases and rheumatic diseases. In this article, we review the role of various human microbiota on the pathogenesis of rheumatic diseases, focusing on spondylarthritis and rheumatoid arthritis.
摘要
类风湿关节炎和脊柱关节炎是最常见的炎症性风湿病。由于人类微生物组参与免疫稳态，因此它有可能成为自身免疫性疾病和风湿病发展的关键因素。在本文中，我们综述了各种人类微生物组在风湿病发病机制中的作用，重点关注脊柱关节炎和类风湿关节炎。
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本文引用的文献
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The Role of Dietary Fiber in Rheumatoid Arthritis Patients: A Feasibility Study.饮食纤维在类风湿关节炎患者中的作用：一项可行性研究。
Nutrients. 2019 Oct 7;11(10):2392. doi: 10.3390/nu11102392.
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Global, regional and national burden of rheumatoid arthritis 1990-2017: a systematic analysis of the Global Burden of Disease study 2017.全球、地区和国家类风湿关节炎负担 1990-2017 年：2017 年全球疾病负担研究的系统分析。
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Oral microbial dysbiosis linked to worsened periodontal condition in rheumatoid arthritis patients.口腔微生物失调与类风湿关节炎患者牙周状况恶化有关。
Sci Rep. 2019 Jun 10;9(1):8379. doi: 10.1038/s41598-019-44674-6.
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Periodontal Health and Oral Microbiota in Patients with Rheumatoid Arthritis.类风湿关节炎患者的牙周健康与口腔微生物群
J Clin Med. 2019 May 8;8(5):630. doi: 10.3390/jcm8050630.
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Periodontal status correlates with anti-citrullinated protein antibodies in first-degree relatives of individuals with rheumatoid arthritis.牙周状况与类风湿关节炎患者一级亲属的抗瓜氨酸化蛋白抗体相关。
J Clin Periodontol. 2019 Jul;46(7):690-698. doi: 10.1111/jcpe.13117. Epub 2019 May 28.
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in individuals at risk for rheumatoid arthritis.在类风湿关节炎风险个体中。
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experimentally induces periodontis and an anti-CCP2-associated arthritis in the rat.实验诱导大鼠牙周炎和抗 CCP2 相关关节炎。
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Variations in oral microbiome profiles in rheumatoid arthritis and osteoarthritis with potential biomarkers for arthritis screening.类风湿关节炎和骨关节炎口腔微生物组谱的变化及关节炎筛查的潜在生物标志物。
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