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胃肠道在非消化系统疾病中的作用:粪便钙卫蛋白的作用是什么?

Gastrointestinal Involvement in Extra-Digestive Disease: Which Is the Role of Fecal Calprotectin?

机构信息

Department of Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.

Department of Internal Medicine, Ospedale San Carlo di Nancy, 00165 Rome, Italy.

出版信息

Medicina (Kaunas). 2022 Oct 2;58(10):1384. doi: 10.3390/medicina58101384.

Abstract

Fecal calprotectin (FC) is a very sensitive marker of inflammation of the gastrointestinal tract. Its clinical utility can be appreciated in both intestinal and extraintestinal diseases. Recent evidence suggests a link between intestinal inflammation and dermatological, rheumatic and neurological diseases. This review focuses on the role of FC in non-gastrointestinal disease, such as rheumatic, dermatologic, neurologic and last but not least SARS-CoV-2 infection.

摘要

粪便钙卫蛋白(FC)是一种非常敏感的胃肠道炎症标志物。其临床应用价值在肠道和肠道外疾病中均有体现。最近的证据表明,肠道炎症与皮肤科、风湿科和神经科疾病之间存在关联。本综述重点介绍了 FC 在非胃肠道疾病中的作用,如风湿科、皮肤科、神经科,最后还介绍了 COVID-19 感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8569/9608771/63f166bb072d/medicina-58-01384-g001.jpg

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