Sharma Monisha, Ong Jason J, Celum Connie, Terris-Prestholt Fern
Department of Global Health, University of Washington, School of Public Health, 908 Jefferson St, Seattle, WA 98104, United States.
Department of Clinical Research and Development, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
EClinicalMedicine. 2020 Nov 30;29-30:100653. doi: 10.1016/j.eclinm.2020.100653. eCollection 2020 Dec.
Understanding variations in HIV testing preferences can help inform optimal combinations of testing services to maximize coverage. We conducted a systematic review of Discrete Choice Experiments (DCEs) eliciting HIV testing preference.
We searched the published literature for papers that conducted DCEs to assess user preferences for HIV testing.
We identified 237 publications; 14 studies conducted in 10 countries met inclusion criteria. Overall, test cost was one of the strongest drivers of preference, with participants preferring free or very low-cost testing. Confidentiality was a salient concern, particularly among key populations and persons who never tested. Participants in resource-limited settings preferred short travel distance and integration of HIV testing with other services. There was substantial heterogeneity across participant characteristics. For example, while women preferred home testing, high-risk groups (e.g. male porters, female bar workers) and men who had not tested in the last year preferred traveling a short distance for testing. HIV self-testing (HIVST) had high acceptability, particularly among those who had never HIV tested, although most users preferred blood-based sample collection over oral swabs. Participants highly valued post-test counselling availability after HIVST.
Overall, participants value low-cost, confidential testing with short travel distance. HIVST is a promising strategy to increase testing coverage but post-test counseling and support should be made available. Educational campaigns to increase familiarity and build confidence in results of oral testing can improve the success of HIVST. DCEs conducted within clinic settings likely have limited generalizability to those not seeking care, particularly for key populations.
了解艾滋病毒检测偏好的差异有助于确定检测服务的最佳组合,以最大限度地扩大覆盖范围。我们对离散选择实验(DCE)进行了系统评价,以了解艾滋病毒检测偏好。
我们在已发表的文献中搜索进行DCE以评估用户对艾滋病毒检测偏好的论文。
我们识别出237篇出版物;在10个国家进行的14项研究符合纳入标准。总体而言,检测成本是偏好的最强驱动因素之一,参与者更喜欢免费或成本极低的检测。保密性是一个突出问题,特别是在关键人群和从未检测过的人群中。资源有限环境中的参与者更喜欢较短的出行距离以及将艾滋病毒检测与其他服务相结合。参与者特征存在很大异质性。例如,女性更喜欢在家检测,而高风险群体(如男性搬运工、女性酒吧工作人员)和过去一年未进行检测的男性更喜欢短距离出行进行检测。艾滋病毒自我检测(HIVST)具有较高的可接受性,特别是在那些从未进行过艾滋病毒检测的人群中,尽管大多数用户更喜欢采集血样而非口腔拭子样本。参与者非常重视HIVST后的检测后咨询服务。
总体而言,参与者重视低成本、保密且出行距离短的检测。HIVST是扩大检测覆盖范围的一项有前景的策略,但应提供检测后咨询和支持。开展教育活动以增加对口腔检测的熟悉度并增强对检测结果的信心,可以提高HIVST的成功率。在诊所环境中进行的DCE对未寻求医疗服务的人群(特别是关键人群)的普遍适用性可能有限。