氯胺酮：目前在急诊科使用的 200 毫克产品是否适用？
Ketamine: Is the current 200 mg product fit for purpose in the emergency department?
机构信息
Pharmacy Department, Austin Health, Melbourne, Victoria, Australia.
Pharmacy Department, Barwon Health, Geelong, Victoria, Australia.
出版信息
Emerg Med Australas. 2021 Feb;33(1):155-156. doi: 10.1111/1742-6723.13695. Epub 2020 Dec 10.
OBJECTIVE
To describe the magnitude of ketamine doses administered in the ED, to identify an appropriate product to minimise risk of administration errors and diversion.
METHODS
Retrospective audit of patients prescribed ketamine in two mixed adult/paediatric EDs over 12 months.
RESULTS
Ketamine was administered to 386 patients (722 doses). The most common dose was ≤20 mg (52.1%), followed by 21-50 mg (30.5%). Overall, 215 patients required one dose only (71 received a dose ≤20 mg), while 299 required no more than two doses.
CONCLUSION
Over three-quarters of ketamine doses were ≤50 mg; therefore, 50 mg in 1 mL may be an appropriate product.
目的
描述急诊科中给予氯胺酮的剂量大小，以确定一种合适的产品来最小化给药错误和滥用的风险。
方法
对两个混合成人/儿科急诊科在 12 个月内开具氯胺酮处方的患者进行回顾性审核。
结果
共给 386 名患者（722 剂）使用了氯胺酮。最常见的剂量是 ≤20mg（52.1%），其次是 21-50mg（30.5%）。总体而言，215 名患者只需使用一剂（71 名患者接受 ≤20mg 剂量），而 299 名患者不需要使用超过两剂。
结论
超过四分之三的氯胺酮剂量是 ≤50mg；因此，1 毫升 50mg 可能是一种合适的产品。
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