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排除 C2 椎体后方骨化韧带并结合前路可控前移位融合治疗颈椎后纵韧带骨化延伸至 C2 节段。

Exclusion of Ossified Ligaments Behind C2 Vertebra Combined with Anterior Controllable Antedisplacement and Fusion for Cervical Ossification of the Posterior Longitudinal Ligament Extending to C2 Segment.

机构信息

Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, China.

Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, China.

出版信息

World Neurosurg. 2021 Feb;146:e1351-e1359. doi: 10.1016/j.wneu.2020.12.015. Epub 2020 Dec 9.

DOI:10.1016/j.wneu.2020.12.015
PMID:33307264
Abstract

OBJECTIVE

We sought to introduce an anterior surgical technique for cervical ossification of posterior longitudinal ligament (OPLL) extending to C2.

METHODS

A total of 29 patients with multilevel OPLL extending to C2 underwent surgery from January 2016 to January 2019. The rationale of our surgical technique is to transect the ossified ligament at the level of C2/3, dividing OPLL into 2 parts. OPLL behind the C2 vertebra is reserved as "focus exclusion," and OPLL below C2 is performed anterior controllable antedisplacement and fusion. Neurologic condition was evaluated using the Japanese Orthopaedic Association scoring system and its improvement ratio. Radiologic assessment included type and extent of OPLL, occupying rate, thickness and length of ossified mass, and curvature of spinal cord. Surgery- and implant-related complications were recorded.

RESULTS

The mean Japanese Orthopaedic Association score increased from 9.4 to 15.8 points at last follow-up, with a significant improvement (P < 0.01). The mean preoperative length of the ossified mass behind C2 was 15.4 mm, and its thickness was 2.2 mm, with no significant progression at last follow-up (15.3 mm and 2.2 mm, P > 0.05). There was also no statistical difference in OPLL thickness at the largest occupying rate level between preoperation and last follow-up (7.4 mm vs. 7.3 mm, P > 0.05). Four patients presented with cerebrospinal fluid leakage, 1 with screw displacement, and 1 with dysphagia.

CONCLUSIONS

For patients with cervical OPLL extending to C2, exclusion of ossified ligaments behind C2 combined with anterior controllable antedisplacement and fusion below C2 is an effective and alternative technique.

摘要

目的

我们旨在介绍一种用于治疗延伸至 C2 的颈椎后纵韧带骨化症(OPLL)的前路手术技术。

方法

2016 年 1 月至 2019 年 1 月,共有 29 例多节段延伸至 C2 的 OPLL 患者接受了手术。我们手术技术的原理是在 C2/3 水平切断骨化的韧带,将 OPLL 分为两部分。C2 椎体后方的 OPLL 被保留为“焦点排除”,C2 以下的 OPLL 则进行前路可控前移位融合。采用日本矫形协会评分系统及其改善率评估神经状况。影像学评估包括 OPLL 的类型和程度、占位率、骨化块的厚度和长度以及脊髓的曲率。记录手术和植入物相关并发症。

结果

末次随访时,日本矫形协会评分从 9.4 分提高到 15.8 分,有显著改善(P < 0.01)。术前 C2 后方骨化块的平均长度为 15.4mm,厚度为 2.2mm,末次随访时无明显进展(15.3mm 和 2.2mm,P > 0.05)。最大占位率水平的 OPLL 厚度在术前和末次随访时也无统计学差异(7.4mm 比 7.3mm,P > 0.05)。4 例患者出现脑脊液漏,1 例患者出现螺钉移位,1 例患者出现吞咽困难。

结论

对于延伸至 C2 的颈椎 OPLL 患者,排除 C2 后方的骨化韧带,并在 C2 以下进行前路可控前移位融合是一种有效且可行的技术。

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