Renal abscess caused by Panton-Valentine leukocidin-producing : report of an unusual case and review of the literature.

BACKGROUND

Renal abscesses are rare and mainly caused by an ascending infection due to Gram-negative microorganisms. We report the first case of a renal abscess caused by Panton-Valentine leukocidin-producing in an immunocompetent patient, and we present a comprehensive review of the literature.

CASE PRESENTATION

A 20-year-old immunocompetent woman had a 2-month history of left-sided back pain, fever and urinary symptoms. Urinalysis showed leukocyturia (19,000/mm) without bacteriuria. Intravenous cefotaxime treatment was initiated. A computed tomographic scan showed a large abscess in the left kidney. Computed tomographic percutaneous drainage was done and cultures of abscess and blood grew methicillin-susceptible Panton-Valentine leukocidin-producing . Treatment was switched to cefazoline and then to clindamycin for 21 days. The patient quickly improved and the abscess was completely resolved 6 months after end of antibiotic treatment.

CONCLUSION

To our knowledge, this is the first report of a renal abscess caused by Panton-Valentine leukocidin-producing Treatment with percutaneous drainage and an antibiotic with toxin inhibiting effect was successful.