Department of Radiology, University of Cincinnati Medical Center, Cincinnati, OH.
Department of Radiology, University of New Mexico, Albuquerque, NM.
Curr Probl Diagn Radiol. 2022 Jan-Feb;51(1):60-72. doi: 10.1067/j.cpradiol.2020.10.013. Epub 2020 Nov 25.
Sarcoidosis is an idiopathic multisystem disorder characterized by noncaseating granulomas. The article focuses on the typical imaging manifestations of sarcoid and the common differentials that need to be included when appropriate. Mistaking a sarcoid-mimicking disease for sarcoid can result in increased patient morbidity and mortality. The pulmonary system is the most common system involved and is typically the best understood by the radiologist, however a deeper knowledge of the pulmonary findings and features of sarcoid in other organ systems is critical. There is a myriad of sarcoid imaging manifestations that can involve every organ system. Often a confidant diagnosis of sarcoid can be made, however a broad differential may need to be considered- differential diagnoses include primary neoplasm, metastatic disease, infectious, and inflammatory etiologies. Radiologist familiarity with the multimodality multisystem imaging findings of sarcoid can help guide clinical management and optimize patient care.
结节病是一种特发性多系统疾病,其特征为非干酪样肉芽肿。本文主要关注结节病的典型影像学表现,以及在适当情况下需要包括的常见鉴别诊断。将结节病样疾病误诊为结节病可能会导致患者发病率和死亡率增加。肺部系统是最常见的受累系统,放射科医生通常对其最了解,但对其他器官系统中结节病的肺部表现和特征有更深入的了解至关重要。有无数种结节病的影像学表现,可以涉及每个器官系统。通常可以做出明确的结节病诊断,但可能需要考虑广泛的鉴别诊断-鉴别诊断包括原发性肿瘤、转移性疾病、感染和炎症病因。放射科医生熟悉结节病的多模态多系统影像学表现有助于指导临床管理和优化患者护理。