Department of Psychology, University of West Bohemia, Faculty of Education, Veleslavinova 42, 30614 Pilsen, Czech Republic; Department of Pedagogy and Psychology, University of South Bohemia, Faculty of Education, Dukelska 9, 37001 Ceske Budejovice, Czech Republic.
Department of Paediatric Neurology, Charles University, Second Faculty of Medicine and Motol University Hospital, Member of the ERN EpiCARE Motol Epilepsy Center, V Uvalu 84, 15006 Prague, Czech Republic.
Epilepsy Behav. 2021 Jan;114(Pt A):107629. doi: 10.1016/j.yebeh.2020.107629. Epub 2020 Dec 9.
In order to introduce a complex system of monitoring and evaluation of the heath-related quality of life (HRQoL) of children and adolescents with epilepsy (CWE) and their families in the Czech Republic, we aimed to validate the Czech versions of two appropriate instruments - the Impact of Pediatric Epilepsy Scale (IPES) and the Quality of Life in Epilepsy Inventory for Adolescents (QOLIE-AD-48).
The verification of the 11-item IPES was carried out in the group of parents of 248 CWE aged 2-18 years. One hundred and thirty-five CWE from the given group aged 11-18 years then completed the 48-item QOLIE-AD-48. Internal consistency, test-retest reliability (with a three-month interval) and the factorial structure of the Czech versions were determined and compared with the original instruments.
We found that the Czech version of the IPES exhibited very good psychometric properties including high internal consistency (Cronbach's alpha, α, of 0.93), high test-retest reliability (intraclass correlation coefficient, ICC, of 0.76) and the same 3-factor structure as the original instrument. The superiority of this 3-factor solution over the alternate 2-factor model proposed for some language versions of the IPES was determined using confirmatory factor analysis. We found 8 items in the Czech version of the QOLIE-AD-48 belonging to original Attitudes towards epilepsy and Social support subscales that do not fit well with the Czech version due to their low correlation with the total score and insufficient test-retest reliability and should be omitted. For the remaining 40 items, we have determined high internal consistency (α = 0.95) and test-retest reliability (ICC = 0.82). Confirmatory factor analysis revealed that the 6-factor solution derived from the original instrument (without two removed subscales) was appropriate for the Czech version. The individual subscales exhibited high internal consistency with α = 0.61-0.91. The external validation of both instruments was confirmed based on a significant correlation between test results and physicians' reports of the characteristics of the child's epilepsy.
The Czech versions of both instruments studied are reliable and valid, and can be used in the next research focusing on the effect of different treatment approaches on the HRQoL of CWE and their families.
为了介绍一个监测和评估捷克儿童和青少年癫痫（CWE）及其家庭健康相关生活质量（HRQoL）的复杂系统，我们旨在验证两个合适工具的捷克语版本——儿科癫痫影响量表（IPES）和青少年癫痫生活质量量表（QOLIE-AD-48）。
对 248 名年龄在 2-18 岁的 CWE 父母进行了 11 项 IPES 的验证。来自同一组的 135 名年龄在 11-18 岁的 CWE 完成了 48 项 QOLIE-AD-48。确定并比较了捷克语版本的内部一致性、测试-重测可靠性（间隔三个月）和因子结构与原始工具。
我们发现，捷克语版的 IPES 具有非常好的心理计量学特性，包括高内部一致性（Cronbach's alpha，α，为 0.93）、高测试-重测可靠性（组内相关系数，ICC，为 0.76）和与原始工具相同的 3 因子结构。使用验证性因子分析确定了该 3 因子解决方案优于 IPES 的某些语言版本提出的替代 2 因子模型的优越性。我们发现，捷克语版的 QOLIE-AD-48 中有 8 项属于原始的对癫痫的态度和社会支持分量表，由于与总分的相关性较低且测试-重测可靠性不足，与捷克语版本不太匹配，应予以删除。对于其余的 40 项，我们确定了高内部一致性（α=0.95）和测试-重测可靠性（ICC=0.82）。验证性因子分析表明，源自原始仪器的 6 因子解决方案（不包括两个删除的分量表）适合捷克语版本。各个分量表的内部一致性较高，α=0.61-0.91。根据测试结果与医生报告的儿童癫痫特征之间的显著相关性，验证了这两种工具的外部有效性。
研究中两种工具的捷克语版本均可靠有效，可用于关注不同治疗方法对 CWE 及其家庭 HRQoL 的影响的进一步研究。
