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癫痫患者睡眠障碍的患病率:一项基于问卷的横断面研究。

Prevalence of sleep disorders in patients with epilepsy: A questionnaire-based cross-sectional study.

机构信息

Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Epilepsy Behav. 2021 Jan;114(Pt A):107635. doi: 10.1016/j.yebeh.2020.107635. Epub 2020 Dec 9.

Abstract

BACKGROUND

Sleep disturbance is a frequent finding in patients with epilepsy. As evaluation of sleep disorders and quality of sleep in patients with epilepsy may provide better management of these patients, we aimed to assess the prevalence of common sleep disorders in patients with epilepsy.

METHODS

Patients with epilepsy referred to an outpatient epilepsy clinic in Tehran during one year were included. Validated Persian questionnaires were used by an interviewer to assess Excessive daytime sleepiness (EDS), Restless leg syndrome (RLS), and insomnia. Also, patients' demographic features and clinical seizure-related characteristics were recorded.

RESULTS

Seventy patients (35 males) aged between 18 and 75 were enrolled. Among patients, 61.4, 35.7, and 28.6% suffered from insomnia, EDS, and RLS, respectively (mild to severe). When considering seizure characteristics, there was no significant correlation between either seizure frequency or its type and the prevalence of sleep disturbance (although sleep disturbance was more common among patients with higher seizure frequency and patients with generalized seizure). Interestingly, age had a positive correlation with EDS.

CONCLUSION

This study showed that sleep disturbance is a common finding in patients with epilepsy, which may become severe in some cases. Taking this into consideration, we suggest that routine evaluation of sleep disorders may help physicians to boost patients' sleep quality.

摘要

背景

睡眠障碍是癫痫患者常见的症状。由于评估癫痫患者的睡眠障碍和睡眠质量可以更好地管理这些患者,我们旨在评估癫痫患者常见睡眠障碍的患病率。

方法

我们纳入了一年内在德黑兰一家癫痫门诊就诊的癫痫患者。访谈者使用经过验证的波斯语问卷评估日间嗜睡(EDS)、不宁腿综合征(RLS)和失眠。同时,记录患者的人口统计学特征和与临床发作相关的特征。

结果

共有 70 名年龄在 18 至 75 岁之间的患者(35 名男性)入组。患者中分别有 61.4%、35.7%和 28.6%患有失眠、EDS 和 RLS(轻度至重度)。考虑到发作特征,发作频率或类型与睡眠障碍的患病率之间没有显著相关性(尽管睡眠障碍在发作频率较高和全身性发作的患者中更为常见)。有趣的是,年龄与 EDS 呈正相关。

结论

本研究表明,睡眠障碍是癫痫患者常见的症状,在某些情况下可能会变得严重。考虑到这一点,我们建议常规评估睡眠障碍可能有助于医生提高患者的睡眠质量。

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