Öztürk Oya, Kabeloğlu Vasfiye, Ataklı Dilek
Neurology Department, University of Health Sciences Bakırköy Prof. Dr. Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Zuhuratbaba Dr Tevfik Sağlam Cd, 34147 Istanbul, Turkey.
Sleep Biol Rhythms. 2022 Mar 24;20(3):413-420. doi: 10.1007/s41105-022-00386-5. eCollection 2022 Jul.
This study aimed to determine the frequency of restless leg syndrome (RLS) and other sleep-related movement disorders and their effects on sleep quality in epilepsy patients. One hundred and twenty-seven epilepsy patients were compared with 115 age-and gender-matched healthy controls. RLS was determined from the clinical characteristics of the patients according to the International RLS Study Group's (IRLSSG) diagnostic criteria. Sleep bruxism was diagnosed based on the International Classification of Sleep Disorders, Third Edition (ICSD-3) criteria. Subjective sleep quality was evaluated with the Pittsburgh Sleep Quality Index (PSQI). Poor sleep quality was more common in the epilepsy group than in the control group (42.5% versus 26.1%; = 0.007). The epilepsy group had significantly higher PSQI total scores than the control group ( = 0.003). The frequency of RLS was higher in epileptic patients than in the control group (13.4% versus 5.2%; = 0.024). There were no significant differences between the patient group and the control group regarding limb movement and bruxism frequency during sleep. The PSQI scores were high in epilepsy patients with RLS compared to those without RLS ( = 0.009). The frequency of habitual snoring, bruxism, and repetitive leg movement in sleep was also high in epilepsy patients with RLS compared to those without RLS ( < 0.05). The prevalence of poor sleep quality and RLS in epilepsy patients is higher than in healthy controls. Our results also show the negative impact of RLS on sleep quality in epilepsy patients. Further confirmatory studies using objective sleep tests are needed to identify the mechanisms underlying the current findings.
本研究旨在确定癫痫患者中不宁腿综合征（RLS）及其他与睡眠相关的运动障碍的发生率及其对睡眠质量的影响。将127例癫痫患者与115例年龄和性别匹配的健康对照者进行比较。根据国际不宁腿综合征研究组（IRLSSG）的诊断标准，从患者的临床特征确定RLS。根据《国际睡眠障碍分类》第三版（ICSD - 3）标准诊断睡眠磨牙症。用匹兹堡睡眠质量指数（PSQI）评估主观睡眠质量。癫痫组睡眠质量差的情况比对照组更常见（42.5%对26.1%；P = 0.007）。癫痫组的PSQI总分显著高于对照组（P = 0.003）。癫痫患者中RLS的发生率高于对照组（13.4%对5.2%；P = 0.024）。患者组和对照组在睡眠期间的肢体运动和磨牙症频率方面无显著差异。与无RLS的癫痫患者相比，有RLS的癫痫患者PSQI评分更高（P = 0.009）。与无RLS的癫痫患者相比，有RLS的癫痫患者在睡眠中习惯性打鼾、磨牙症和腿部重复运动的频率也更高（P < 0.05）。癫痫患者中睡眠质量差和RLS的患病率高于健康对照者。我们的结果还显示RLS对癫痫患者睡眠质量有负面影响。需要使用客观睡眠测试进行进一步的验证性研究，以确定当前研究结果背后的机制。
