Sayag J, Lagrange B
C.H.U. Timone Service Dermatologique, Marseille.
Allerg Immunol (Paris). 1987 Sep;19(7):294-302.
The purpose of oral food challenges is to detect food intolerance. Challenges of food additives and drugs are not often used in children. The authors report methods and protocols that they used for food, food additives and contaminants and emphasize the potential dangers of these tests. Atopic diseases and chronic urticaria are the principal indications. Cow's milk, eggs and fish are the allergens that are most often incriminated. Oral challenges are only to be done as part of an integrated investigation together with skin tests, in vitro tests and a study of intestinal permeability. Food avoidance and therapy should be decided after the challenge data are available.
口服食物激发试验的目的是检测食物不耐受。食物添加剂和药物激发试验在儿童中并不常用。作者报告了他们用于食物、食物添加剂和污染物的方法及方案，并强调了这些检测的潜在风险。特应性疾病和慢性荨麻疹是主要适应症。牛奶、鸡蛋和鱼类是最常涉及的过敏原。口服激发试验应仅作为与皮肤试验、体外试验及肠道通透性研究相结合的综合调查的一部分来进行。应在获得激发试验数据后再决定食物回避和治疗方案。
