Texas A&M Health Science Center College of Medicine, Bryan, Texas, U.S.A.
Department of Neurology, Houston Methodist Hospital, Houston, Texas, U.S.A.
J Clin Neurophysiol. 2021 Mar 1;38(2):e5-e10. doi: 10.1097/WNP.0000000000000783.
Neurological manifestations of coronavirus disease 2019 most commonly present in severe cases and range from mild complications, such as headache and dizziness, to severe complications, such as encephalopathy and acute cerebrovascular disease. Seizures, however, are an underreported neurological manifestation of this disease. We present three critically ill coronavirus disease 2019 patients with EEG monitoring who developed new-onset seizures and encephalopathy up to three-and-a-half weeks after symptom onset. There are several speculated etiologies for the development of new-onset seizures; however, the pathogenic mechanism remains unknown. Testing of coronavirus disease 2019 in the cerebrospinal fluid in addition to extensive research on neurological manifestations is warranted.
新型冠状病毒病 2019 的神经系统表现最常出现在重症病例中，范围从轻度并发症，如头痛和头晕，到严重并发症，如脑病和急性脑血管病。然而，癫痫发作是这种疾病被低估的一种神经系统表现。我们报告了 3 例接受脑电图监测的重症新型冠状病毒病 2019 患者，他们在症状出现后长达 3 周半的时间内出现新发癫痫发作和脑病。有几种推测的新发性癫痫发作的发病机制；然而，其发病机制尚不清楚。除了对神经系统表现进行广泛研究外，还需要对新型冠状病毒病 2019 进行脑脊液检测。
