岛征对脑出血血肿扩大预测意义的 Meta 分析。
A Meta-analysis of the Predictive Significance of the Island Sign for Hematoma Expansion in Intracerebral Hemorrhage.
机构信息
The School Of Clinical Medicine, Fujian Medical University, Fuzhou City, China; Department of Neurosurgery, First Affiliated Hospital of Xiamen University, Xiamen City, China.
Department of Neurosurgery, First Affiliated Hospital of Xiamen University, Xiamen City, China.
出版信息
World Neurosurg. 2021 Mar;147:23-28. doi: 10.1016/j.wneu.2020.12.024. Epub 2020 Dec 13.
BACKGROUND
The island sign of non-contrast computed tomography is a risk factor for hematoma expansion (HE) after spontaneous intracerebral hemorrhage, but has inconsistent conclusions. A meta-analysis was performed to investigate the predictive accuracy of island sign for HE.
METHODS
A systematic review of published literature on island sign and hematoma expansion was conducted. The pooled sensitivity, specificity, and summary receiver operating characteristics curve (SROC) were generated. The publication bias was assessed by Deeks' funnel plot asymmetry test.
RESULTS
Nine studies with a total of 2939 patients were included in the present study. The pooled sensitivity and specificity of island sign for predicting hematoma expansion was 0.50 and 0.89, respectively. The area under the curve was 0.73 in the SROC curve. There was no significant publication bias.
CONCLUSIONS
This meta-analysis suggests that island sign of non-contrast computed tomography has a good predictive accuracy for hematoma enlargement in intracerebral hemorrhage.
背景
非对比 CT 的岛征是自发性脑出血后血肿扩大（HE）的一个危险因素，但结论并不一致。因此进行了一项荟萃分析，以调查岛征对 HE 的预测准确性。
方法
对岛征和血肿扩大的已发表文献进行系统综述。生成汇总的敏感性、特异性和综合受试者工作特征曲线（SROC）。通过 Deeks 漏斗图不对称检验评估发表偏倚。
结果
本研究共纳入 9 项研究，总计 2939 例患者。岛征预测血肿扩大的汇总敏感性和特异性分别为 0.50 和 0.89，SROC 曲线下面积为 0.73。没有显著的发表偏倚。
结论
这项荟萃分析表明，非对比 CT 的岛征对脑出血血肿扩大具有良好的预测准确性。
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