与新型冠状病毒肺炎相关的急性播散性脑脊髓炎
Acute disseminated encephalomyelitis (ADEM) associated with COVID-19.
作者信息
Langley Lawrence, Zeicu Claudia, Whitton Louise, Pauls Mathilde
机构信息
University College Hospital, London, UK
University College Hospital, London, UK.
出版信息
BMJ Case Rep. 2020 Dec 13;13(12):e239597. doi: 10.1136/bcr-2020-239597.
Abstract
A 53-year-old man admitted to the critical care secondary to respiratory failure due to COVID-19 developed agitation and global hypotonia. Brain MRI revealed bilateral hyperintense lesions throughout the brain and cerebrospinal fluid identified oligoclonal bands. Intravenous high-dose glucocorticoids were administered followed by an oral tapering dose and the patient clinically improved. Acute disseminated encephalomyelitis should be considered in patients with COVID-19 who present with altered mentation and polyfocal neurological deficits.
摘要
一名53岁男性因新型冠状病毒肺炎（COVID-19）导致呼吸衰竭入住重症监护病房，出现躁动和全身性肌张力减退。脑部磁共振成像（MRI）显示全脑双侧高信号病变，脑脊液检查发现寡克隆带。给予静脉高剂量糖皮质激素治疗，随后口服逐渐减量，患者临床症状改善。对于出现精神状态改变和多灶性神经功能缺损的COVID-19患者，应考虑急性播散性脑脊髓炎。
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