J Vis Exp. 2020 Dec 15(166). doi: 10.3791/6453.
An erratum was issued for: Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells. NMuMG was mislabeled as cancer cells. NMuMG cells are non-transformed epithelial breast cells established from a mouse mammary gland. NMuMG cells are frequently used as a model system to investigate TGF-β-induced epithelial to mesenchymal transition (EMT). EMT is induced by TGF-β in premalignant human MCF 10A-RAS (M2) cells and mouse MMTV-PyMT breast cancer cell line. The article has been updated to reflect this.
《研究TGF-β信号传导及TGF-β诱导的乳腺癌和正常细胞上皮-间质转化》。NMuMG被错误标记为癌细胞。NMuMG细胞是从小鼠乳腺建立的未转化上皮乳腺细胞。NMuMG细胞经常被用作研究TGF-β诱导的上皮-间质转化（EMT）的模型系统。TGF-β可在癌前人类MCF 10A-RAS（M2）细胞和小鼠MMTV-PyMT乳腺癌细胞系中诱导EMT。本文已更新以反映这一点。
