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妊娠和哺乳期的化脓性汗腺炎:药物安全性综述。

Pregnancy and breastfeeding in hidradenitis suppurativa: A review of medication safety.

机构信息

David Geffen School of Medicine, University of California, Los Angeles, California, USA.

Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

出版信息

Dermatol Ther. 2021 Jan;34(1):e14674. doi: 10.1111/dth.14674. Epub 2020 Dec 25.

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory disease that disproportionately affects women of childbearing age. Pregnancy influences HS severity for many women, thus diligent continued management throughout pregnancy and postpartum may be required. Herein, we provide an updated review of pregnancy and lactation safety data for HS medications, including topical antiseptic washes, topical and systemic antibiotics, biologic and nonbiologic immunomodulators, immunosuppressants, adjunct medical therapies, and pain medications, to help guide risk-benefit discussions between providers and HS patients.

摘要

化脓性汗腺炎(HS)是一种慢性炎症性疾病,不成比例地影响生育年龄的妇女。怀孕会影响许多妇女的 HS 严重程度,因此可能需要在整个怀孕期间和产后进行持续的治疗。在此,我们对 HS 药物的妊娠和哺乳安全性数据进行了更新,包括局部防腐洗液、局部和全身抗生素、生物和非生物免疫调节剂、免疫抑制剂、辅助治疗和止痛药物,以帮助提供者和 HS 患者进行风险效益讨论。

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