以噻吨-9-酮作为光氧化还原催化剂的可见光诱导镍催化的P（O）-C（sp）偶联反应
Visible-Light-Induced Nickel-Catalyzed P(O)-C(sp) Coupling Using Thioxanthen-9-one as a Photoredox Catalysis.
作者信息
Zhu Da-Liang, Jiang Shan, Wu Qi, Wang Hao, Chai Lu-Lu, Li Hai-Yan, Li Hong-Xi
机构信息
College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.
Analysis and Testing Center, Soochow University, Suzhou 215123, China.
出版信息
Org Lett. 2021 Jan 1;23(1):160-165. doi: 10.1021/acs.orglett.0c03892. Epub 2020 Dec 15.
An efficient method has been developed for photocatalytic P(O)-C(sp) coupling of (hetero)aryl halides with H-phosphine oxides or H-phosphites under the irradiation of visible light or sunlight. The thioxanthen-9-one/nickel dual catalysis mediates this phosphonylation to give arylphosphine oxides and arylphosphonates in moderate to excellent yields. This transformation is widely tolerant to a range of functional groups and proceeds efficiently on a gram scale.
已开发出一种高效方法，用于在可见光或太阳光照射下，使（杂）芳基卤化物与H-膦氧化物或亚磷酸酯进行光催化P（O）-C（sp）偶联反应。噻吨-9-酮/镍双催化介导该膦酰化反应，以中等至优异的产率得到芳基膦氧化物和芳基膦酸酯。这种转化对一系列官能团具有广泛的耐受性，并且在克级规模上能高效进行。
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