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褐藻黄素的药理活性研究进展。

Advances in Studies on the Pharmacological Activities of Fucoxanthin.

机构信息

Marine College, Shandong University, Weihai 264209, China.

Test Center for Agri-Products Quality of Jinan, Jinan 250316, China.

出版信息

Mar Drugs. 2020 Dec 11;18(12):634. doi: 10.3390/md18120634.

Abstract

Fucoxanthin is a natural carotenoid derived mostly from many species of marine brown algae. It is characterized by small molecular weight, is chemically active, can be easily oxidized, and has diverse biological activities, thus protecting cell components from ROS. Fucoxanthin inhibits the proliferation of a variety of cancer cells, promotes weight loss, acts as an antioxidant and anti-inflammatory agent, interacts with the intestinal flora to protect intestinal health, prevents organ fibrosis, and exerts a multitude of other beneficial effects. Thus, fucoxanthin has a wide range of applications and broad prospects. This review focuses primarily on the latest progress in research on its pharmacological activity and underlying mechanisms.

摘要

岩藻黄质是一种天然类胡萝卜素,主要来源于多种海洋褐藻。其分子量小、化学活性高、易氧化,具有多种生物学活性,从而保护细胞成分免受 ROS 损伤。岩藻黄质可抑制多种癌细胞增殖,促进体重减轻,具有抗氧化和抗炎作用,与肠道菌群相互作用以保护肠道健康,预防器官纤维化,并发挥多种其他有益作用。因此,岩藻黄质具有广泛的应用前景。本文主要综述了其药理活性及作用机制的最新研究进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f05/7763821/d5fc91bff2f9/marinedrugs-18-00634-g001.jpg

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