Sun Xiaowen, Xu Ying, Zhao Lili, Yan Hongxue, Wang Shuhui, Wang Dongfeng
College of Food Science and Engineering, Ocean University of China Qingdao 266003 People's Republic of China
State Key Laboratory of Bioactive Seaweed Substances, Qingdao Brightmoon Seaweed Group Co Ltd Qingdao 266400 People's Republic of China.
RSC Adv. 2018 Oct 15;8(61):35139-35149. doi: 10.1039/c8ra05621h. eCollection 2018 Oct 10.
Fucoxanthin is a major marine carotenoid with many biological activities. It is well known that fucoxanthin is unstable to heat and acid due to its polyunsaturated structure. Another defect of fucoxanthin is the low bioavailability and all these drawbacks make it limited in the food industry. In order to improve its stability and intestinal absorption, fucoxanthin was encapsulated with biopolymers by spray drying in this study. All the microspheres we prepared had a spherical shape with encapsulation efficiencies (EE) ranging from 86.48% to 97.06%. A heat stability test showed that maltodextrin (MD), gum arabic (GA) and whey protein isolate (WPI) improved the thermal stability of fucoxanthin. The degradation kinetics of the loaded fucoxanthin encapsulated with biopolymers also indicated that GA and MD had a better protective effect on fucoxanthin. The encapsulated fucoxanthin degradation rate within MD, GA, WPI and gelatin (GEL) followed second-order kinetics and their half-life ( ) was 92.6 d, 99.8 d, 50.9 d and 69.3 d, respectively. The simulated digestion test suggested that MD, GA and WPI effectively protected fucoxanthin in the gastric acid environment, meanwhile increasing the release rate of fucoxanthin in the intestinal tract.
岩藻黄质是一种具有多种生物活性的主要海洋类胡萝卜素。众所周知，由于其多不饱和结构，岩藻黄质对热和酸不稳定。岩藻黄质的另一个缺陷是生物利用度低，所有这些缺点使其在食品工业中的应用受到限制。为了提高其稳定性和肠道吸收，本研究通过喷雾干燥法用生物聚合物对岩藻黄质进行包封。我们制备的所有微球均呈球形，包封率（EE）在86.48%至97.06%之间。热稳定性测试表明，麦芽糊精（MD）、阿拉伯胶（GA）和乳清蛋白分离物（WPI）提高了岩藻黄质的热稳定性。用生物聚合物包封的负载型岩藻黄质的降解动力学也表明，GA和MD对岩藻黄质具有更好的保护作用。MD、GA、WPI和明胶（GEL）中包封的岩藻黄质降解速率符合二级动力学，其半衰期分别为92.6天、99.8天、50.9天和69.3天。模拟消化试验表明，MD、GA和WPI在胃酸环境中有效地保护了岩藻黄质，同时提高了岩藻黄质在肠道中的释放速率。
